Coverart for item
The Resource Application of systematic review methods in an overall strategy for evaluating low-dose toxicity from endocrine active chemicals, Committee on Endocrine-Related Low-Dose Toxicity, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies

Application of systematic review methods in an overall strategy for evaluating low-dose toxicity from endocrine active chemicals, Committee on Endocrine-Related Low-Dose Toxicity, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies

Label
Application of systematic review methods in an overall strategy for evaluating low-dose toxicity from endocrine active chemicals
Title
Application of systematic review methods in an overall strategy for evaluating low-dose toxicity from endocrine active chemicals
Statement of responsibility
Committee on Endocrine-Related Low-Dose Toxicity, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies
Contributor
Author
Subject
Genre
Language
eng
Summary
"To safeguard public health, the US Environmental Protection Agency (EPA) must keep abreast of new scientific information and emerging technologies so that it can apply them to regulatory decision-making. For decades the agency has dealt with questions about what animal-testing data to use to make predictions about human health hazards, how to perform dose-response extrapolations, how to identify and protect susceptible subpopulations, and how to address uncertainties. As alternatives to traditional toxicity testing have emerged, the agency has been faced with additional questions about how to incorporate data from such tests into its chemical assessments and whether such tests can replace some traditional testing methods. Endocrine active chemicals (EACs) have raised concerns that traditional toxicity-testing protocols might be inadequate to identify all potential hazards to human health because they have the ability to modulate normal hormone function, and small alterations in hormone concentrations, particularly during sensitive life stages, can have lasting and significant effects. To address concerns about potential human health effects from EACs at low doses, this report develops a strategy to evaluate the evidence for such low-dose effects"--Publisher's description
Cataloging source
SCB
Dewey number
616.4
Illustrations
illustrations
Index
no index present
LC call number
RC649
LC item number
.A67 2017
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
WK 100
http://library.link/vocab/relatedWorkOrContributorDate
2016
http://library.link/vocab/relatedWorkOrContributorName
  • National Academies of Sciences, Engineering, and Medicine (U.S.)
  • Workshop on Potential Case Studies for Unraveling Endocrine-Related Low-Dose Toxicity
http://library.link/vocab/subjectName
  • Endocrine toxicology
  • Endocrine disrupting chemicals
  • Systematic reviews (Medical research)
  • Endocrine Glands
  • HEALTH & FITNESS
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Endocrine toxicology
  • Systematic reviews (Medical research)
Label
Application of systematic review methods in an overall strategy for evaluating low-dose toxicity from endocrine active chemicals, Committee on Endocrine-Related Low-Dose Toxicity, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies
Instantiates
Publication
Copyright
Note
  • "A consensus study report of the National Academies of Sciences, Engineering, Medicine."
  • Title from PDF title page (National Academies Press, viewed July 24, 2017)
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Strategy for evaluating low-dose effects -- Phthalates and male reproductive-tract development -- Effect of polybrominated diphenyl ethers on neurodevelopment -- Lessons learned and reflections on the statement of task -- Appendix A: Biosketches of the Committee on Endocrine-Related Low-Dose Toxicity -- Appendix B; Workshop on Potential Case Studies for Unraveling Endocrine-Related Low-Dose Toxicity -- Appendix C: Supporting materials for the phthalate (animal) systematic review -- Appendix D: Supporting materials for the phthalate (human) systematic review -- Appendix E: Supporting materials for the PBDE (animal) systematic review -- Appendix F: Supporting materials for the PBDE (human) systematic review
Control code
994612372
Extent
1 online resource (xviii, 404 pages)
Form of item
online
Isbn
9780309458634
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)994612372
Label
Application of systematic review methods in an overall strategy for evaluating low-dose toxicity from endocrine active chemicals, Committee on Endocrine-Related Low-Dose Toxicity, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies
Publication
Copyright
Note
  • "A consensus study report of the National Academies of Sciences, Engineering, Medicine."
  • Title from PDF title page (National Academies Press, viewed July 24, 2017)
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Strategy for evaluating low-dose effects -- Phthalates and male reproductive-tract development -- Effect of polybrominated diphenyl ethers on neurodevelopment -- Lessons learned and reflections on the statement of task -- Appendix A: Biosketches of the Committee on Endocrine-Related Low-Dose Toxicity -- Appendix B; Workshop on Potential Case Studies for Unraveling Endocrine-Related Low-Dose Toxicity -- Appendix C: Supporting materials for the phthalate (animal) systematic review -- Appendix D: Supporting materials for the phthalate (human) systematic review -- Appendix E: Supporting materials for the PBDE (animal) systematic review -- Appendix F: Supporting materials for the PBDE (human) systematic review
Control code
994612372
Extent
1 online resource (xviii, 404 pages)
Form of item
online
Isbn
9780309458634
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)994612372

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