Coverart for item
The Resource Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer

Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer

Label
Biophysical approaches determining ligand binding to biomolecular targets
Title
Biophysical approaches determining ligand binding to biomolecular targets
Statement of responsibility
editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer
Contributor
Subject
Language
eng
Summary
The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational approaches to drug discovery and design. This book reviews the latest advances in the application of biophysics to the study of ligand binding. It provides a complete overview of current techniques to identify ligands, characterise their binding sites and understand their binding mechanisms. Particular emphasis is given to the combined use of different techniques and their relative strengths and weaknesses. Consistency in the way each technique is described makes it easy for readers to select the most suitable protocol for their research. The introduction explains why some techniques are more suitable than others and emphasizes the possible synergies between them. The following chapters, all written by a specialist in the particular technique, focus on each method individually. The book finishes by describing how several complimentary techniques can be used together for maximum effectiveness. This book is suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry. Biologists and chemists will also find it a useful introduction to the techniques available
Member of
Cataloging source
UKRSC
Dewey number
572.33
Index
no index present
LC call number
QP517.L54
LC item number
B56 2010
Literary form
non fiction
Nature of contents
dictionaries
http://library.link/vocab/relatedWorkOrContributorName
  • Podjarny, A. D
  • Dejaegere, Annick P
  • Kieffer, Bruno
Series statement
RSC biomolecular sciences
http://library.link/vocab/subjectName
  • Ligand binding (Biochemistry)
  • SCIENCE
  • Ligand binding (Biochemistry)
Label
Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer
Instantiates
Publication
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
725827817
Dimensions
unknown
Extent
1 online resource
Form of item
online
Isbn
9781849730099
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1039/9781849732666
http://library.link/vocab/ext/overdrive/overdriveId
t3394
Specific material designation
remote
System control number
(OCoLC)725827817
Label
Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer
Publication
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
725827817
Dimensions
unknown
Extent
1 online resource
Form of item
online
Isbn
9781849730099
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
10.1039/9781849732666
http://library.link/vocab/ext/overdrive/overdriveId
t3394
Specific material designation
remote
System control number
(OCoLC)725827817

Library Locations

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      1 University Blvd, St. Louis, MO, 63121, US
      38.710138 -90.311107
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