The Resource Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer
Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer
Resource Information
The item Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.
This item is available to borrow from 1 library branch.
- Summary
- The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational approaches to drug discovery and design. This book reviews the latest advances in the application of biophysics to the study of ligand binding. It provides a complete overview of current techniques to identify ligands, characterise their binding sites and understand their binding mechanisms. Particular emphasis is given to the combined use of different techniques and their relative strengths and weaknesses. Consistency in the way each technique is described makes it easy for readers to select the most suitable protocol for their research. The introduction explains why some techniques are more suitable than others and emphasizes the possible synergies between them. The following chapters, all written by a specialist in the particular technique, focus on each method individually. The book finishes by describing how several complimentary techniques can be used together for maximum effectiveness. This book is suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry. Biologists and chemists will also find it a useful introduction to the techniques available
- Language
- eng
- Label
- Biophysical approaches determining ligand binding to biomolecular targets
- Title
- Biophysical approaches determining ligand binding to biomolecular targets
- Statement of responsibility
- editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer
- Language
- eng
- Summary
- The binding of small ligands to biological molecules is central to most aspects of biological function. The past twenty years has seen the development of an increasing armoury of biophysical methods that not only detect such binding, but also provide varying degrees of information about the kinetics, thermodynamics and structural aspects of the process. These methods have received increasing attention with the growth in more rational approaches to drug discovery and design. This book reviews the latest advances in the application of biophysics to the study of ligand binding. It provides a complete overview of current techniques to identify ligands, characterise their binding sites and understand their binding mechanisms. Particular emphasis is given to the combined use of different techniques and their relative strengths and weaknesses. Consistency in the way each technique is described makes it easy for readers to select the most suitable protocol for their research. The introduction explains why some techniques are more suitable than others and emphasizes the possible synergies between them. The following chapters, all written by a specialist in the particular technique, focus on each method individually. The book finishes by describing how several complimentary techniques can be used together for maximum effectiveness. This book is suitable for biomolecular scientists at graduate or post-doctoral level in academia and industry. Biologists and chemists will also find it a useful introduction to the techniques available
- Cataloging source
- UKRSC
- Dewey number
- 572.33
- Index
- no index present
- LC call number
- QP517.L54
- LC item number
- B56 2010
- Literary form
- non fiction
- Nature of contents
- dictionaries
- http://library.link/vocab/relatedWorkOrContributorName
-
- Podjarny, A. D
- Dejaegere, Annick P
- Kieffer, Bruno
- Series statement
- RSC biomolecular sciences
- http://library.link/vocab/subjectName
-
- Ligand binding (Biochemistry)
- SCIENCE
- Ligand binding (Biochemistry)
- Label
- Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 725827817
- Dimensions
- unknown
- Extent
- 1 online resource
- Form of item
- online
- Isbn
- 9781849730099
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1039/9781849732666
- http://library.link/vocab/ext/overdrive/overdriveId
- t3394
- Specific material designation
- remote
- System control number
- (OCoLC)725827817
- Label
- Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 725827817
- Dimensions
- unknown
- Extent
- 1 online resource
- Form of item
- online
- Isbn
- 9781849730099
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other control number
- 10.1039/9781849732666
- http://library.link/vocab/ext/overdrive/overdriveId
- t3394
- Specific material designation
- remote
- System control number
- (OCoLC)725827817
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.umsl.edu/portal/Biophysical-approaches-determining-ligand-binding/h6BYHTUuniY/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.umsl.edu/portal/Biophysical-approaches-determining-ligand-binding/h6BYHTUuniY/">Biophysical approaches determining ligand binding to biomolecular targets, editors, Alberto Podjarny, Annick P. Dejaegere and Bruno Kieffer</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.umsl.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.umsl.edu/">University of Missouri-St. Louis Libraries</a></span></span></span></span></div>
