The Resource Caspases : roles and significance in cell death and disease, Jeffrey Warren, editor
Caspases : roles and significance in cell death and disease, Jeffrey Warren, editor
Resource Information
The item Caspases : roles and significance in cell death and disease, Jeffrey Warren, editor represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item Caspases : roles and significance in cell death and disease, Jeffrey Warren, editor represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.
This item is available to borrow from 1 library branch.
- Extent
- 1 online resource.
- Contents
-
- Preface; Chapter 1; Caspases: A Driver in Programmed Cell Death; Abstract; 1. Introduction; 2. History of Caspases; 3. Role of Caspases in Apoptosis; 4. Initiator Caspases; 5. Executioner Caspases; 6. Apoptosis Pathways; 6.1. The Extrinsic Route of Apoptosis; 6.1.1. Death Receptor (DR) Pathway of Apoptosis; 6.1.2. Ligand Death Receptor; 6.2. The Intrinsic Route of Apoptosis; 7. Types of Caspase; 7.1. Caspase-1; 7.2. Caspase-2; 7.3. Caspase-3; 7.4. Caspase-6; 7.5. Caspase-7; 7.6. Caspase-8; 7.7. Caspase-9; 7.8. Caspase-10; 7.9. Caspase-12; 7.10. Caspase-14
- 8. Comparison of Caspase-1, -4, -59. Cellular Proliferation; 9.1. Cellular Differentiation; 9.2. Apoptosis and Immuno-Suppression; 10. General Caspase Inhibition In Vivo; 11. Caspases in Sub-Cellular Compartments; Conclusion and Future Perspectives; References; Chapter 2; Caspases Importance in Cell Death and Disease; Abstract; 1. Introduction; 2. Apoptosis; 3. Necrosis; 4. Caspases Structure; 5. Apoptotic Role; 6. Non Apoptotic Role; 7. Immune Function; 8. An Inflammatory Microenvironment; 9. Mechanisms of Substrate Recognition; 10. Human Caspases; 11. Activity of Caspases in Inflammation
- 12. Function of Pattern-Recognition Receptors13. Caspases in Proliferation; 14. Cell Migration; 15. Cell Differentiation; 16. Dimerisation; 17. Cleavage; 18. Caspases in Human Disease; 18.1. Cancer; 18.2. Inflammatory Diseases; 18.3. Gout; 18.4. Cryopyrin-Associated Periodic Syndromes; 18.5. Type 2 Diabetes; 18.6. Familial Mediterranean Fever; 18.7. Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, and Acne Syndrome; 18.8. Hyperimmunoglobulinemia D with Periodic Fever Syndrome; 18.9. Trypanosoma Cruzi Infection; Conclusion and Future Perspectives; References; Chapter 3
- The Role of Executioner Caspases in Cancer Formation and MaintenanceAbstract; 1. Introduction; 2. Caspase Family; 2.1. Structural Considerations of Human Executioner Caspases; 2.2. Caspase Substrates; 2.3. Caspase Active Sites; 2.4. Caspase Exosites; 2.5. Caspase Dimerization; 2.6. Executioner Caspase Activation by Proteolysis; 2.7. Caspase Allosteric Sites; 2.8. Post-Translational Modification; 2.8.1. Ubiquitylation; 2.8.2. Phosphorylation; 2.8.3. Nitrosylation; 2.8.4. Acetylation; 2.9. Cellular Localization; 3. Caspase Gene Expression; 3.1. Splice Variants of Executioner Caspases
- 4. Caspase Deficiencies in Cancer4.1. Expression of Caspase Inhibitory Pathways -- Upstream (MOMP) and Downstream (IAPs); 5. Mammalian Models Interrogating Pathophysiological Roles of Executioner Caspases; Conclusion; References; Supplementary Resources; Biographical Sketch; Chapter 4; The Unknown Caspase: The Role of Caspase-14 in Cell Death and Disease; Abstract; Introduction; Caspase-14: Discovery and Structure; The Role of Caspase-14 in Cell Death; The Role of Caspase-14 in Disease; Caspase-14 Protects Against Common Skin Conditions; Caspase-14 Is Implicated in Disorders of the Eye
- Isbn
- 9781536102604
- Label
- Caspases : roles and significance in cell death and disease
- Title
- Caspases
- Title remainder
- roles and significance in cell death and disease
- Statement of responsibility
- Jeffrey Warren, editor
- Language
- eng
- Cataloging source
- DLC
- Dewey number
- 571.9/36
- Illustrations
- illustrations
- Index
- index present
- LC call number
- QH671
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- http://library.link/vocab/relatedWorkOrContributorName
- Warren, Jeffrey S.
- Series statement
- Cell biology research progress
- http://library.link/vocab/subjectName
-
- Apoptosis
- Cell death
- SCIENCE / Life Sciences / Anatomy & Physiology
- Apoptosis
- Cell death
- Label
- Caspases : roles and significance in cell death and disease, Jeffrey Warren, editor
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Preface; Chapter 1; Caspases: A Driver in Programmed Cell Death; Abstract; 1. Introduction; 2. History of Caspases; 3. Role of Caspases in Apoptosis; 4. Initiator Caspases; 5. Executioner Caspases; 6. Apoptosis Pathways; 6.1. The Extrinsic Route of Apoptosis; 6.1.1. Death Receptor (DR) Pathway of Apoptosis; 6.1.2. Ligand Death Receptor; 6.2. The Intrinsic Route of Apoptosis; 7. Types of Caspase; 7.1. Caspase-1; 7.2. Caspase-2; 7.3. Caspase-3; 7.4. Caspase-6; 7.5. Caspase-7; 7.6. Caspase-8; 7.7. Caspase-9; 7.8. Caspase-10; 7.9. Caspase-12; 7.10. Caspase-14
- 8. Comparison of Caspase-1, -4, -59. Cellular Proliferation; 9.1. Cellular Differentiation; 9.2. Apoptosis and Immuno-Suppression; 10. General Caspase Inhibition In Vivo; 11. Caspases in Sub-Cellular Compartments; Conclusion and Future Perspectives; References; Chapter 2; Caspases Importance in Cell Death and Disease; Abstract; 1. Introduction; 2. Apoptosis; 3. Necrosis; 4. Caspases Structure; 5. Apoptotic Role; 6. Non Apoptotic Role; 7. Immune Function; 8. An Inflammatory Microenvironment; 9. Mechanisms of Substrate Recognition; 10. Human Caspases; 11. Activity of Caspases in Inflammation
- 12. Function of Pattern-Recognition Receptors13. Caspases in Proliferation; 14. Cell Migration; 15. Cell Differentiation; 16. Dimerisation; 17. Cleavage; 18. Caspases in Human Disease; 18.1. Cancer; 18.2. Inflammatory Diseases; 18.3. Gout; 18.4. Cryopyrin-Associated Periodic Syndromes; 18.5. Type 2 Diabetes; 18.6. Familial Mediterranean Fever; 18.7. Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, and Acne Syndrome; 18.8. Hyperimmunoglobulinemia D with Periodic Fever Syndrome; 18.9. Trypanosoma Cruzi Infection; Conclusion and Future Perspectives; References; Chapter 3
- The Role of Executioner Caspases in Cancer Formation and MaintenanceAbstract; 1. Introduction; 2. Caspase Family; 2.1. Structural Considerations of Human Executioner Caspases; 2.2. Caspase Substrates; 2.3. Caspase Active Sites; 2.4. Caspase Exosites; 2.5. Caspase Dimerization; 2.6. Executioner Caspase Activation by Proteolysis; 2.7. Caspase Allosteric Sites; 2.8. Post-Translational Modification; 2.8.1. Ubiquitylation; 2.8.2. Phosphorylation; 2.8.3. Nitrosylation; 2.8.4. Acetylation; 2.9. Cellular Localization; 3. Caspase Gene Expression; 3.1. Splice Variants of Executioner Caspases
- 4. Caspase Deficiencies in Cancer4.1. Expression of Caspase Inhibitory Pathways -- Upstream (MOMP) and Downstream (IAPs); 5. Mammalian Models Interrogating Pathophysiological Roles of Executioner Caspases; Conclusion; References; Supplementary Resources; Biographical Sketch; Chapter 4; The Unknown Caspase: The Role of Caspase-14 in Cell Death and Disease; Abstract; Introduction; Caspase-14: Discovery and Structure; The Role of Caspase-14 in Cell Death; The Role of Caspase-14 in Disease; Caspase-14 Protects Against Common Skin Conditions; Caspase-14 Is Implicated in Disorders of the Eye
- Control code
- 959373869
- Extent
- 1 online resource.
- Form of item
- online
- Isbn
- 9781536102604
- Lccn
- 2016044447
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)959373869
- Label
- Caspases : roles and significance in cell death and disease, Jeffrey Warren, editor
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- Preface; Chapter 1; Caspases: A Driver in Programmed Cell Death; Abstract; 1. Introduction; 2. History of Caspases; 3. Role of Caspases in Apoptosis; 4. Initiator Caspases; 5. Executioner Caspases; 6. Apoptosis Pathways; 6.1. The Extrinsic Route of Apoptosis; 6.1.1. Death Receptor (DR) Pathway of Apoptosis; 6.1.2. Ligand Death Receptor; 6.2. The Intrinsic Route of Apoptosis; 7. Types of Caspase; 7.1. Caspase-1; 7.2. Caspase-2; 7.3. Caspase-3; 7.4. Caspase-6; 7.5. Caspase-7; 7.6. Caspase-8; 7.7. Caspase-9; 7.8. Caspase-10; 7.9. Caspase-12; 7.10. Caspase-14
- 8. Comparison of Caspase-1, -4, -59. Cellular Proliferation; 9.1. Cellular Differentiation; 9.2. Apoptosis and Immuno-Suppression; 10. General Caspase Inhibition In Vivo; 11. Caspases in Sub-Cellular Compartments; Conclusion and Future Perspectives; References; Chapter 2; Caspases Importance in Cell Death and Disease; Abstract; 1. Introduction; 2. Apoptosis; 3. Necrosis; 4. Caspases Structure; 5. Apoptotic Role; 6. Non Apoptotic Role; 7. Immune Function; 8. An Inflammatory Microenvironment; 9. Mechanisms of Substrate Recognition; 10. Human Caspases; 11. Activity of Caspases in Inflammation
- 12. Function of Pattern-Recognition Receptors13. Caspases in Proliferation; 14. Cell Migration; 15. Cell Differentiation; 16. Dimerisation; 17. Cleavage; 18. Caspases in Human Disease; 18.1. Cancer; 18.2. Inflammatory Diseases; 18.3. Gout; 18.4. Cryopyrin-Associated Periodic Syndromes; 18.5. Type 2 Diabetes; 18.6. Familial Mediterranean Fever; 18.7. Pyogenic Sterile Arthritis, Pyoderma Gangrenosum, and Acne Syndrome; 18.8. Hyperimmunoglobulinemia D with Periodic Fever Syndrome; 18.9. Trypanosoma Cruzi Infection; Conclusion and Future Perspectives; References; Chapter 3
- The Role of Executioner Caspases in Cancer Formation and MaintenanceAbstract; 1. Introduction; 2. Caspase Family; 2.1. Structural Considerations of Human Executioner Caspases; 2.2. Caspase Substrates; 2.3. Caspase Active Sites; 2.4. Caspase Exosites; 2.5. Caspase Dimerization; 2.6. Executioner Caspase Activation by Proteolysis; 2.7. Caspase Allosteric Sites; 2.8. Post-Translational Modification; 2.8.1. Ubiquitylation; 2.8.2. Phosphorylation; 2.8.3. Nitrosylation; 2.8.4. Acetylation; 2.9. Cellular Localization; 3. Caspase Gene Expression; 3.1. Splice Variants of Executioner Caspases
- 4. Caspase Deficiencies in Cancer4.1. Expression of Caspase Inhibitory Pathways -- Upstream (MOMP) and Downstream (IAPs); 5. Mammalian Models Interrogating Pathophysiological Roles of Executioner Caspases; Conclusion; References; Supplementary Resources; Biographical Sketch; Chapter 4; The Unknown Caspase: The Role of Caspase-14 in Cell Death and Disease; Abstract; Introduction; Caspase-14: Discovery and Structure; The Role of Caspase-14 in Cell Death; The Role of Caspase-14 in Disease; Caspase-14 Protects Against Common Skin Conditions; Caspase-14 Is Implicated in Disorders of the Eye
- Control code
- 959373869
- Extent
- 1 online resource.
- Form of item
- online
- Isbn
- 9781536102604
- Lccn
- 2016044447
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)959373869
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