The Resource Caveolin-1 A scaffold for microcompartmental organization of membrane-associated glycolysis, by Mark J. Hernandez Vizcaino, (electronic resource)

Caveolin-1 A scaffold for microcompartmental organization of membrane-associated glycolysis, by Mark J. Hernandez Vizcaino, (electronic resource)

Label
Caveolin-1 A scaffold for microcompartmental organization of membrane-associated glycolysis
Title
Caveolin-1 A scaffold for microcompartmental organization of membrane-associated glycolysis
Statement of responsibility
by Mark J. Hernandez Vizcaino
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
The role of membrane caveolae in the compartmentation of membrane glycolytic metabolism indicates a pivotal role of caveolin in the localization of glycolytic enzymes to this membrane domain. This dissertation demonstrates the following about the role of protein scaffold caveolin-1 (CAV-1) in the compartmentation of membrane glycolytic metabolism. 1) CAV-1 a scaffold of phosphofructokinase (PFK) can also target other glycolytic enzymes such as aldolase, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and pyruvate kinase (PK) to the membrane of lymphocytes transfected with caveolin-1 (CAV-1). 2) CAV-1 is subject to regulation during enhanced glycolytic metabolism in astrocytes after 24 hour exposure to high NH4Cl. 3) The caveolin-1 scaffolding domain (CSD) is essential for the targeting of glycolytic enzyme PFK to the cell membrane in the vascular smooth muscle cell line A7r5. This dissertation addressed these three fundamental roles of caveolin-1 that support the essential role of caveolins in the organization of membrane associated glycolytic metabolism
Cataloging source
MMU
http://library.link/vocab/creatorDate
1979-
http://library.link/vocab/creatorName
Hernandez, Mark J.
Degree
Ph. D.
Dissertation year
2007.
Granting institution
University of Missouri-Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Hardin, Christopher D.
http://library.link/vocab/subjectName
  • Caveolin 1
  • Glycolysis
  • Cell Membrane
  • Myocytes, Smooth Muscle
Target audience
specialized
Label
Caveolin-1 A scaffold for microcompartmental organization of membrane-associated glycolysis, by Mark J. Hernandez Vizcaino, (electronic resource)
Instantiates
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Vita
  • "August 2007"
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
182537955
Dimensions
unknown
Form of item
electronic
Governing access note
Access is limited to the campuses of the University of Missouri
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)182537955
System details
Mode of access: World Wide Web
Label
Caveolin-1 A scaffold for microcompartmental organization of membrane-associated glycolysis, by Mark J. Hernandez Vizcaino, (electronic resource)
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Vita
  • "August 2007"
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
182537955
Dimensions
unknown
Form of item
electronic
Governing access note
Access is limited to the campuses of the University of Missouri
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)182537955
System details
Mode of access: World Wide Web

Library Locations

    • Thomas Jefferson LibraryBorrow it
      1 University Blvd, St. Louis, MO, 63121, US
      38.710138 -90.311107
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