Coverart for item
The Resource Controlled human Inhalation-exposure studies at EPA, Committee on Assessing Toxicologic Risks to Human Subjects Used in Controlled Exposure Studies of Environmental Pollutants, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies ; a report of The National Academies of Sciences, Engineering, Medicine, (electronic resource)

Controlled human Inhalation-exposure studies at EPA, Committee on Assessing Toxicologic Risks to Human Subjects Used in Controlled Exposure Studies of Environmental Pollutants, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies ; a report of The National Academies of Sciences, Engineering, Medicine, (electronic resource)

Label
Controlled human Inhalation-exposure studies at EPA
Title
Controlled human Inhalation-exposure studies at EPA
Statement of responsibility
Committee on Assessing Toxicologic Risks to Human Subjects Used in Controlled Exposure Studies of Environmental Pollutants, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies ; a report of The National Academies of Sciences, Engineering, Medicine
Title variation
Controlled human Inhalation-exposure studies at Environmental Protection Agency
Creator
Subject
Language
eng
Summary
"The U.S. Environmental Protection Agency (EPA) has a mission and regulatory responsibility to protect human health and the environment. EPA's pursuit of that goal includes a variety of research activities involving human subjects, such as epidemiologic studies and surveys. Those research activities also involve studies of individuals who volunteer to be exposed to air pollutants intentionally in controlled laboratory settings so that measurements can be made of transient and reversible biomarker or physiologic responses to those exposures that can indicate pathways of toxicity and mechanisms of air-pollution responses. The results of those controlled human inhalation exposure (CHIE) studies, also referred to as human clinical studies or human challenge studies, are used to inform policy decisions and help establish or revise standards to protect public health and improve air quality. Controlled Human Inhalation-Exposure Studies at EPA addresses scientific issues and provides guidance on the conduct of CHIE studies. This report assesses the utility of CHIE studies to inform and reduce uncertainties in setting air-pollution standards to protect public health and assess whether continuation of such studies is warranted. It also evaluates the potential health risks to test subjects who participated in recent studies of air pollutants at EPA's clinical research facility"--
Assigning source
Publisher's description
Cataloging source
TKN
Dewey number
363.738
LC call number
RC720
LC item number
.N38 2017
http://bibfra.me/vocab/lite/organizationName
National Academies of Sciences, Engineering, and Medicine (U.S.)
http://library.link/vocab/subjectName
  • United States
  • Pulmonary toxicology
  • Pollutants
  • United States
  • Respiratory System
  • Air Pollutants
  • Inhalation Exposure
  • Healthy Volunteers
  • Nontherapeutic Human Experimentation
  • United States
  • United States
  • Pollutants
  • Pulmonary toxicology
Label
Controlled human Inhalation-exposure studies at EPA, Committee on Assessing Toxicologic Risks to Human Subjects Used in Controlled Exposure Studies of Environmental Pollutants, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies ; a report of The National Academies of Sciences, Engineering, Medicine, (electronic resource)
Instantiates
Publication
Bibliography note
Includes bibliographical references (pages 95-105)
Contents
Introduction -- Foundational aspects of human-subjects research -- Value of controlled human inhalation exposure studies -- Assessment of controlled human inhalation exposure studies at EPA and associated adverse events -- The continued conduct of controlled human inhalation exposure studies by EPA -- Characterizing risks to subjects in controlled human inhalation exposure studies -- Communication about informed consent in controlled human inhalation exposure studies -- Reference -- Appendix A: Biographical information on the Committee on Assessing Toxicologic Risks to Human Subjects Used in Controlled Exposure Studies of Environmental Pollutants -- Appendix B: Public information-Gathering sessions -- Appendix C: Assessment of eight controlled human exposure studies
Control code
OCM1bookssj0001975220
Dimensions
unknown
Isbn
9780309452496
Lccn
2017446455
Specific material designation
remote
System control number
(WaSeSS)bookssj0001975220
Label
Controlled human Inhalation-exposure studies at EPA, Committee on Assessing Toxicologic Risks to Human Subjects Used in Controlled Exposure Studies of Environmental Pollutants, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies ; a report of The National Academies of Sciences, Engineering, Medicine, (electronic resource)
Publication
Bibliography note
Includes bibliographical references (pages 95-105)
Contents
Introduction -- Foundational aspects of human-subjects research -- Value of controlled human inhalation exposure studies -- Assessment of controlled human inhalation exposure studies at EPA and associated adverse events -- The continued conduct of controlled human inhalation exposure studies by EPA -- Characterizing risks to subjects in controlled human inhalation exposure studies -- Communication about informed consent in controlled human inhalation exposure studies -- Reference -- Appendix A: Biographical information on the Committee on Assessing Toxicologic Risks to Human Subjects Used in Controlled Exposure Studies of Environmental Pollutants -- Appendix B: Public information-Gathering sessions -- Appendix C: Assessment of eight controlled human exposure studies
Control code
OCM1bookssj0001975220
Dimensions
unknown
Isbn
9780309452496
Lccn
2017446455
Specific material designation
remote
System control number
(WaSeSS)bookssj0001975220

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