The Resource DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li
DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li
Resource Information
The item DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.
This item is available to borrow from 1 library branch.
- Summary
- DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology
- Language
- eng
- Extent
- 1 online resource (xi, 118 pages)
- Contents
-
- ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages
- ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse
- ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis
- ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis
- 4.4. More information on SDL global optimization
- ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion
- ch. 6. General discussion and future directions
- Isbn
- 9786612441240
- Label
- DNA microarray technology and data analysis in cancer research
- Title
- DNA microarray technology and data analysis in cancer research
- Statement of responsibility
- Shaoguang Li, Dongguang Li
- Subject
-
- Cancer cells -- Growth | Regulation
- Cancer cells -- Growth | Regulation
- Chemistry Techniques, Analytical
- DNA microarrays
- DNA microarrays
- Data Interpretation, Statistical
- Decision Support Techniques
- Disease
- Electronic books
- Gene Expression
- Genetic Phenomena
- Genetic Techniques
- HEALTH & FITNESS -- Diseases | Cancer
- Investigative Techniques
- MEDICAL -- Oncology
- Microarray Analysis
- Microchip Analytical Procedures
- Molecular Probe Techniques
- Natural Science Disciplines
- Neoplasms
- Nucleic Acid Hybridization
- Oligonucleotide Array Sequence Analysis
- Oligonucleotide Array Sequence Analysis -- methods
- Phenomena and Processes
- Research
- Science
- Sequence Analysis
- Methods
- Language
- eng
- Summary
- DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology
- Cataloging source
- E7B
- http://library.link/vocab/creatorName
- Li, Shaoguang
- Dewey number
- 616.994071
- Illustrations
- illustrations
- Index
- index present
- Language note
- English
- LC call number
- RC269.7
- LC item number
- .L5 2008eb
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- NLM call number
- QZ 206
- NLM item number
- .L693d 2008
- http://library.link/vocab/relatedWorkOrContributorName
- Li, Dongguang
- http://library.link/vocab/subjectName
-
- Cancer cells
- DNA microarrays
- Genetic Phenomena
- Disease
- Methods
- Sequence Analysis
- Oligonucleotide Array Sequence Analysis
- Oligonucleotide Array Sequence Analysis
- Neoplasms
- Data Interpretation, Statistical
- Research
- Gene Expression
- Science
- Investigative Techniques
- Molecular Probe Techniques
- Microarray Analysis
- Nucleic Acid Hybridization
- Decision Support Techniques
- Genetic Techniques
- Microchip Analytical Procedures
- Natural Science Disciplines
- Chemistry Techniques, Analytical
- Phenomena and Processes
- MEDICAL
- HEALTH & FITNESS
- Cancer cells
- DNA microarrays
- Label
- DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li
- Bibliography note
- Includes bibliographical references (pages 105-115) and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages -- ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse -- ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis -- ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis -- 4.4. More information on SDL global optimization -- ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion -- ch. 6. General discussion and future directions
- Control code
- 647853583
- Dimensions
- unknown
- Extent
- 1 online resource (xi, 118 pages)
- Form of item
- online
- Isbn
- 9786612441240
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations (some color)
- Specific material designation
- remote
- System control number
- (OCoLC)647853583
- Label
- DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li
- Bibliography note
- Includes bibliographical references (pages 105-115) and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
- ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages -- ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse -- ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis -- ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis -- 4.4. More information on SDL global optimization -- ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion -- ch. 6. General discussion and future directions
- Control code
- 647853583
- Dimensions
- unknown
- Extent
- 1 online resource (xi, 118 pages)
- Form of item
- online
- Isbn
- 9786612441240
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations (some color)
- Specific material designation
- remote
- System control number
- (OCoLC)647853583
Subject
- Cancer cells -- Growth | Regulation
- Cancer cells -- Growth | Regulation
- Chemistry Techniques, Analytical
- DNA microarrays
- DNA microarrays
- Data Interpretation, Statistical
- Decision Support Techniques
- Disease
- Electronic books
- Gene Expression
- Genetic Phenomena
- Genetic Techniques
- HEALTH & FITNESS -- Diseases | Cancer
- Investigative Techniques
- MEDICAL -- Oncology
- Microarray Analysis
- Microchip Analytical Procedures
- Molecular Probe Techniques
- Natural Science Disciplines
- Neoplasms
- Nucleic Acid Hybridization
- Oligonucleotide Array Sequence Analysis
- Oligonucleotide Array Sequence Analysis -- methods
- Phenomena and Processes
- Research
- Science
- Sequence Analysis
- Methods
Genre
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