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The Resource DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li

DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li

Label
DNA microarray technology and data analysis in cancer research
Title
DNA microarray technology and data analysis in cancer research
Statement of responsibility
Shaoguang Li, Dongguang Li
Creator
Contributor
Subject
Genre
Language
eng
Summary
DNA microarray technology has become a useful technique in gene expression analysis for the development of new diagnostic tools and for the identification of disease genes and therapeutic targets for human cancers. Appropriate control for DNA microarray experiment and reliable analysis of the array data are key to performing the assay and utilizing the data correctly. The most difficult challenge has been the lack of a powerful method to analyze the data for all genes (more than 30,000 genes) simultaneously and to use the microarray data in a decision-making process. In this book, the authors describe DNA microarray technology and data analysis by pointing out current advantages and disadvantages of the technique and available analytical methods. Crucially, new ideas and analytical methods based on the authors' own experience in DNA microarray study and analysis are introduced. It is believed that this new way of interpreting and analyzing microarray data will bring us closer to success in decision-making using the information obtained through the DNA microarray technology
Member of
Cataloging source
E7B
http://library.link/vocab/creatorName
Li, Shaoguang
Dewey number
616.994071
Illustrations
illustrations
Index
index present
Language note
English
LC call number
RC269.7
LC item number
.L5 2008eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QZ 206
NLM item number
.L693d 2008
http://library.link/vocab/relatedWorkOrContributorName
Li, Dongguang
http://library.link/vocab/subjectName
  • Cancer cells
  • DNA microarrays
  • Genetic Phenomena
  • Disease
  • Methods
  • Sequence Analysis
  • Oligonucleotide Array Sequence Analysis
  • Oligonucleotide Array Sequence Analysis
  • Neoplasms
  • Data Interpretation, Statistical
  • Research
  • Gene Expression
  • Science
  • Investigative Techniques
  • Molecular Probe Techniques
  • Microarray Analysis
  • Nucleic Acid Hybridization
  • Decision Support Techniques
  • Genetic Techniques
  • Microchip Analytical Procedures
  • Natural Science Disciplines
  • Chemistry Techniques, Analytical
  • Phenomena and Processes
  • MEDICAL
  • HEALTH & FITNESS
  • Cancer cells
  • DNA microarrays
Label
DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li
Instantiates
Publication
Bibliography note
Includes bibliographical references (pages 105-115) and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages -- ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse -- ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis -- ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis -- 4.4. More information on SDL global optimization -- ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion -- ch. 6. General discussion and future directions
Control code
647853583
Dimensions
unknown
Extent
1 online resource (xi, 118 pages)
Form of item
online
Isbn
9786612441240
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)647853583
Label
DNA microarray technology and data analysis in cancer research, Shaoguang Li, Dongguang Li
Publication
Bibliography note
Includes bibliographical references (pages 105-115) and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
ch. 1. DNA microarray technology. 1.1. Experimental procedure. 1.2. Experimental design. 1.3. Quality control. 1.4. Interpretation of DNA microarray data. 1.5. Advantages and disadvantages -- ch. 2. Applications of DNA microarray technology in cancer research. 2.1. Solid tumors. 2.2. Blood cancers. 2.3. Our DNA microarray study using mouse -- ch. 3. Current analytical methods of DNA microarray data. 3.1. Experimental design. 3.2. Method. 3.3. Quality control diagnostics. 3.4. Statistical analysis. 3.5. Coefficient of variation analysis -- ch. 4. A novel method for DNA microarray data analysis : SDL global optimization method. 4.1. Research subjects. 4.2. Experimental design. 4.3. Fold change analysis -- 4.4. More information on SDL global optimization -- ch. 5. Applications of the SDL global optimization method in DNA microarray data analysis. 5.1. Leukemia cell line study. 5.2. Analyses of publicly available human microarray data. 5.3. Overall methodology. 5.4. Experimental results. 5.5. Discussion. 5.6. Conclusion -- ch. 6. General discussion and future directions
Control code
647853583
Dimensions
unknown
Extent
1 online resource (xi, 118 pages)
Form of item
online
Isbn
9786612441240
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)647853583

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