The Resource Development of gold nanoparticle conjugated polyethylene terephthalate for improved biocompatibility in hernia repair materials, by Ona Whelove

Development of gold nanoparticle conjugated polyethylene terephthalate for improved biocompatibility in hernia repair materials, by Ona Whelove

Label
Development of gold nanoparticle conjugated polyethylene terephthalate for improved biocompatibility in hernia repair materials
Title
Development of gold nanoparticle conjugated polyethylene terephthalate for improved biocompatibility in hernia repair materials
Statement of responsibility
by Ona Whelove
Creator
Contributor
Author
Thesis advisor
Subject
Genre
Language
eng
Summary
Synthetic biomaterials are currently a popular choice for use in many surgical soft tissue repair applications. Polyethylene terephthalate (PET) is an example of such material that has been used, more specifically, for hernia repair. PET mesh is one of the top choices for hernia repair due to its flexibility, porosity, mechanical strength, and relative inertness; however, explanted PET hernia meshes have shown signs of degradation, which can cause complications with tissue compatibility and increase the chance for recurrence when used as a biomaterial implant for extended periods of time. In this study, the effects of modifying the PET surface, through chemical functionalization and gold nanoparticle (AuNP) conjugation, were investigated. Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and differential scanning calorimetry (DSC) were used to characterize the modified PET in comparison to pristine PET. Results from these studies showed that the PET mesh surface could be successfully functionalized and cross-linked with AuNP while maintaining the physical and thermal properties of pristine PET. Cell culture assays, including WST-1 cell proliferation assays, reactive oxygen species (ROS) assays, and antimicrobial studies, were performed to investigate in vitro performances of the modified PET mesh
Cataloging source
MUU
http://library.link/vocab/creatorName
Whelove, Ona
Degree
M.S.
Dissertation note
Thesis
Dissertation year
2010.
Government publication
government publication of a state province territory dependency etc
Granting institution
University of Missouri--Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Grant, Sheila Ann
Label
Development of gold nanoparticle conjugated polyethylene terephthalate for improved biocompatibility in hernia repair materials, by Ona Whelove
Instantiates
Publication
Note
  • "December 2010."
  • "A Thesis presented to the Faculty of the Graduate School at the University of Missouri In Partial Fulfillment of the Requirements for the Degree Master of Science."
  • Thesis supervisor: Dr. Sheila Grant
Bibliography note
Includes bibliographical references (pages 86-89)
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier.
Content category
text
Content type code
txt
Content type MARC source
rdacontent.
Control code
900615341
Extent
1 online resource (xi, 89 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia.
Media type code
c
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)900615341
Label
Development of gold nanoparticle conjugated polyethylene terephthalate for improved biocompatibility in hernia repair materials, by Ona Whelove
Publication
Note
  • "December 2010."
  • "A Thesis presented to the Faculty of the Graduate School at the University of Missouri In Partial Fulfillment of the Requirements for the Degree Master of Science."
  • Thesis supervisor: Dr. Sheila Grant
Bibliography note
Includes bibliographical references (pages 86-89)
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier.
Content category
text
Content type code
txt
Content type MARC source
rdacontent.
Control code
900615341
Extent
1 online resource (xi, 89 pages)
Form of item
online
Media category
computer
Media MARC source
rdamedia.
Media type code
c
Other physical details
illustrations (some color)
Specific material designation
remote
System control number
(OCoLC)900615341

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