The Resource Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by University of Connecticut/Hartford Evidence-based Practice Center ; investigators, Olivia J. Phung [and others], (electronic resource)
Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by University of Connecticut/Hartford Evidence-based Practice Center ; investigators, Olivia J. Phung [and others], (electronic resource)
Resource Information
The item Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by University of Connecticut/Hartford Evidence-based Practice Center ; investigators, Olivia J. Phung [and others], (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.This item is available to borrow from all library branches.
Resource Information
The item Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by University of Connecticut/Hartford Evidence-based Practice Center ; investigators, Olivia J. Phung [and others], (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.
This item is available to borrow from all library branches.
- Summary
- OBJECTIVES: This is an evidence report prepared by the University of Connecticut/Hartford Hospital Evidence-based Practice Center (EPC) examining the benefits and harms associated with using recombinant human growth hormone (rhGH) in patients with cystic fibrosis (CF). CONCLUSIONS: rhGH improved almost all intermediate measures of pulmonary function, height, and weight in patients with CF. Improvements in bone mineral content are also promising. However, with the exception of hospitalizations, the benefits on final health outcomes cannot be directly determined at this time. In the relatively low doses used in CF patients for a time period of 6 to 12 months, rhGH therapy may worsen short term markers of glucose control but may not impact long terms glucose control. The increase in IGF-I with rhGH therapy is above a threshold thought to increase the risk of malignancy but the strength of this marker in determining malignancy is not firmly established
- Language
- eng
- Extent
- 1 online resource
- Note
- "October 2010."
- Label
- Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis
- Title
- Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis
- Statement of responsibility
- prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by University of Connecticut/Hartford Evidence-based Practice Center ; investigators, Olivia J. Phung [and others]
- Language
- eng
- Summary
- OBJECTIVES: This is an evidence report prepared by the University of Connecticut/Hartford Hospital Evidence-based Practice Center (EPC) examining the benefits and harms associated with using recombinant human growth hormone (rhGH) in patients with cystic fibrosis (CF). CONCLUSIONS: rhGH improved almost all intermediate measures of pulmonary function, height, and weight in patients with CF. Improvements in bone mineral content are also promising. However, with the exception of hospitalizations, the benefits on final health outcomes cannot be directly determined at this time. In the relatively low doses used in CF patients for a time period of 6 to 12 months, rhGH therapy may worsen short term markers of glucose control but may not impact long terms glucose control. The increase in IGF-I with rhGH therapy is above a threshold thought to increase the risk of malignancy but the strength of this marker in determining malignancy is not firmly established
- Cataloging source
- NLM
- Funding information
- Contract No. 290-2007-10067-I.
- Government publication
- federal national government publication
- Illustrations
- illustrations
- Index
- no index present
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- NLM call number
- WI 820
- http://library.link/vocab/relatedWorkOrContributorName
-
- Phung, Olivia J
- United States
- University of Connecticut-Hartford Hospital Evidence-based Practice Center
- Effective Health Care Program (U.S.)
- Series statement
-
- Comparative effectiveness review
- AHRQ publication
- Series volume
-
- no. 23
- no. 11-EHC003-EF
- http://library.link/vocab/subjectName
-
- Cystic Fibrosis
- Evidence-Based Medicine
- Human Growth Hormone
- http://bibfra.me/vocab/relation/supportingbody
- RzTDSdffmEM
- Label
- Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by University of Connecticut/Hartford Evidence-based Practice Center ; investigators, Olivia J. Phung [and others], (electronic resource)
- Note
- "October 2010."
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
- txt
- Content type MARC source
- rdacontent
- Control code
- 780224026
- Extent
- 1 online resource
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
- c
- Other physical details
- illustrations
- Specific material designation
- remote
- System control number
- (OCoLC)780224026
- Label
- Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by University of Connecticut/Hartford Evidence-based Practice Center ; investigators, Olivia J. Phung [and others], (electronic resource)
- Note
- "October 2010."
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
- cr
- Carrier MARC source
- rdacarrier
- Content category
- text
- Content type code
- txt
- Content type MARC source
- rdacontent
- Control code
- 780224026
- Extent
- 1 online resource
- Form of item
- online
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
- c
- Other physical details
- illustrations
- Specific material designation
- remote
- System control number
- (OCoLC)780224026
Library Locations
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St. Louis Mercantile LibraryBorrow it1 University Blvd, St. Louis, MO, 63121, US38.710138 -90.311107
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University of Missouri-St. Louis Libraries DepositoryBorrow it2908 Lemone Blvd, Columbia, MO, 65201, US38.919360 -92.291620
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Ward E Barnes Education LibraryBorrow it8001 Natural Bridge Rd, St. Louis, MO, 63121, US38.707079 -90.311355
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.umsl.edu/portal/Effectiveness-of-recombinant-human-growth-hormone/ij7lOX8Qb44/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.umsl.edu/portal/Effectiveness-of-recombinant-human-growth-hormone/ij7lOX8Qb44/">Effectiveness of recombinant human growth hormone (rhGH) in the treatment of patients with cystic fibrosis, prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by University of Connecticut/Hartford Evidence-based Practice Center ; investigators, Olivia J. Phung [and others], (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.umsl.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.umsl.edu/">University of Missouri-St. Louis Libraries</a></span></span></span></span></div>
