The Resource Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system, by Maren Bell Jones, (electronic resource)
Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system, by Maren Bell Jones, (electronic resource)
Resource Information
The item Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system, by Maren Bell Jones, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.This item is available to borrow from all library branches.
Resource Information
The item Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system, by Maren Bell Jones, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.
This item is available to borrow from all library branches.
- Summary
- Recent studies have indicated that a number of ubiquitous chemicals found in the environment are linked to a myriad of health concerns, including reproductive abnormalities and increases in infertility, cancer, and obesity via their actions as exogenous hormones. Because of the importance of evaluating the effects of these chemicals in living model organisms, maintaining the sensitivity of various bioassays as indicators of hormone action is critical. One source of variability is the isoflavones (a type of hormonally active phytoestrogen) in soy-based rodent diets. If the background levels of these diets are too high, they can interfere with the body's response to an endocrine disrupting chemical. Our studies showed that variability within the phytoestrogen levels in different brands and lots of diets can cause changes in sensitive bioassays such as the fetal estradiol levels, uterotrophic response to estrogen, the timing of the onset of puberty, and the amount of gonadal fat as adults. In addition, maintaining the animals on various brands with varying background levels of phytoestrogens yielded different endpoints when the animals were exposed to a prenatal dose of the known endocrine disrupting chemical diethylstilbestrol. We conclude that sensitive endpoints used to determine the effects of environmental endocrine disrupting chemicals are affected by varying background levels of phytoestrogens
- Language
- eng
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Title from title screen of research.pdf file (viewed on October 29, 2007)
- Vita
- Label
- Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system
- Title
- Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system
- Statement of responsibility
- by Maren Bell Jones
- Title variation
- Effects and interactions of diet and endocrine disrupting chemicals on the mouse reproductive system
- Language
- eng
- Summary
- Recent studies have indicated that a number of ubiquitous chemicals found in the environment are linked to a myriad of health concerns, including reproductive abnormalities and increases in infertility, cancer, and obesity via their actions as exogenous hormones. Because of the importance of evaluating the effects of these chemicals in living model organisms, maintaining the sensitivity of various bioassays as indicators of hormone action is critical. One source of variability is the isoflavones (a type of hormonally active phytoestrogen) in soy-based rodent diets. If the background levels of these diets are too high, they can interfere with the body's response to an endocrine disrupting chemical. Our studies showed that variability within the phytoestrogen levels in different brands and lots of diets can cause changes in sensitive bioassays such as the fetal estradiol levels, uterotrophic response to estrogen, the timing of the onset of puberty, and the amount of gonadal fat as adults. In addition, maintaining the animals on various brands with varying background levels of phytoestrogens yielded different endpoints when the animals were exposed to a prenatal dose of the known endocrine disrupting chemical diethylstilbestrol. We conclude that sensitive endpoints used to determine the effects of environmental endocrine disrupting chemicals are affected by varying background levels of phytoestrogens
- Cataloging source
- MUU
- http://library.link/vocab/creatorDate
- 1982-
- http://library.link/vocab/creatorName
- Jones, Maren Bell
- Degree
- M.A.
- Dissertation year
- 2007.
- Granting institution
- University of Missouri-Columbia
- Illustrations
- illustrations
- Index
- no index present
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- theses
- http://library.link/vocab/relatedWorkOrContributorName
- Vom Saal, Frederick S.
- http://library.link/vocab/subjectName
-
- Endocrine toxicology
- Endocrine glands
- Mice
- Target audience
- specialized
- Label
- Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system, by Maren Bell Jones, (electronic resource)
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Title from title screen of research.pdf file (viewed on October 29, 2007)
- Vita
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- mixed
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 179693198
- Dimensions
- unknown
- Form of item
- electronic
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)179693198
- System details
- Mode of access: World Wide Web
- Label
- Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system, by Maren Bell Jones, (electronic resource)
- Note
-
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Title from title screen of research.pdf file (viewed on October 29, 2007)
- Vita
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- mixed
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 179693198
- Dimensions
- unknown
- Form of item
- electronic
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)179693198
- System details
- Mode of access: World Wide Web
Library Locations
-
St. Louis Mercantile LibraryBorrow it1 University Blvd, St. Louis, MO, 63121, US38.710138 -90.311107
-
-
University ArchivesBorrow it703 Lewis Hall, Columbia, MO, 65211, US
-
University of Missouri-St. Louis Libraries DepositoryBorrow it2908 Lemone Blvd, Columbia, MO, 65201, US38.919360 -92.291620
-
University of Missouri-St. Louis Libraries DepositoryBorrow it2908 Lemone Blvd, Columbia, MO, 65201, US38.919360 -92.291620
-
Ward E Barnes Education LibraryBorrow it8001 Natural Bridge Rd, St. Louis, MO, 63121, US38.707079 -90.311355
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.umsl.edu/portal/Effects-and-interactions-of-endocrine-disrupting/cEfRUS31808/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.umsl.edu/portal/Effects-and-interactions-of-endocrine-disrupting/cEfRUS31808/">Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system, by Maren Bell Jones, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.umsl.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.umsl.edu/">University of Missouri-St. Louis Libraries</a></span></span></span></span></div>
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.umsl.edu/portal/Effects-and-interactions-of-endocrine-disrupting/cEfRUS31808/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.umsl.edu/portal/Effects-and-interactions-of-endocrine-disrupting/cEfRUS31808/">Effects and interactions of endocrine disrupting chemicals and diet on the mouse reproductive system, by Maren Bell Jones, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.umsl.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.umsl.edu/">University of Missouri-St. Louis Libraries</a></span></span></span></span></div>
