The Resource Essentials of glycobiology, edited by Ajit Varki [and eleven others]

Essentials of glycobiology, edited by Ajit Varki [and eleven others]

Label
Essentials of glycobiology
Title
Essentials of glycobiology
Statement of responsibility
edited by Ajit Varki [and eleven others]
Contributor
Editor
Subject
Language
eng
Summary
"Defined in the broadest sense, Glycobiology is the study of the structure, biosynthesis, biology, and evolution of saccharides (sugar chains or glycans) that are widely distributed in nature in all living life forms. Glycobiology is now one of the more rapidly growing fields in the natural sciences, with broad relevance to many areas of basic research, biomedicine, and biotechnology. The field includes the chemistry of carbohydrates, the enzymology of glycan formation and degradation, the recognition of glycans by specific proteins, roles of glycans in complex biological systems, and their analysis or manipulation by various techniques. The third edition of this primary textbook in the field continues in the prior tradition, seeking to provide basic overview of Glycobiology, directed towards the advanced undergraduate or the beginning graduate-level student of molecular and cellular biology and biomedicine. While efforts have been made to avoid a major increase in overall length of the text, substantial changes and improvements include the following: broader focus on all lineages of life forms in nature; wider range of topics, ranging from biology and medicine to chemistry and materials science; expanded international editorial board representing a wider range of expertise; wider range of contributing authors with expertise in specific areas; greatly expanded monosaccharide symbol nomenclature for the representation of glycans; and greater attention to informatics, and relevance to exploration of the glycome"--Publisher's description
Cataloging source
MMU
Dewey number
572/.68
Illustrations
illustrations
Index
no index present
LC call number
QP552.G59
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QU 55.5
http://library.link/vocab/relatedWorkOrContributorName
Varki, Ajit
http://library.link/vocab/subjectName
  • Glycoproteins
  • Glycosylation
  • Glycomics
  • Molecular biology
  • Glycoproteins
  • Glycosyltransferases
  • Glycosylation
  • Glycomics
  • Glycomics
  • Glycoproteins
  • Glycosylation
  • Molecular biology
Label
Essentials of glycobiology, edited by Ajit Varki [and eleven others]
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
  • text
  • still image
Content type code
  • txt
  • sti
Content type MARC source
  • rdacontent
  • rdacontent
Contents
General principles. Historical background and overview -- Monosaccharide diversity -- Oligosaccharides and polysaccharides -- Cellular organization of glycosylation -- Glycosylation precursors -- Glycosyltransferases and glycan-processing enzymes -- Biological functions of glycans -- A genomic view of glycobiology -- Structure and biosynthesis. N-glycans -- O-GalNAc glycans -- Glycosphingolipids -- Glycosylphosphatidylinositol anchors -- Other classes of eukaryotic glycans -- Structures common to different glycans -- Sialic acids and other nonulosonic acids -- Hyaluronan -- Proteoglycans and sulfated glycosaminoglycans -- Nucleocytoplasmic glycosylation -- The O-GlcNAc modification -- Glycans in evolution and development. Evolution of glycan diversity -- Eubacteria -- Archaea -- Fungi -- Viridiplantae and algae -- Nematoda -- Arthropoda -- Deuterostomes -- Glycan-binding proteins. Discovery and classification of glycan-binding protein -- Principles of glycan recognition -- Structural biology of glycan recognition -- R-type lectins -- L-type lectins -- P-type lectins -- C-type lectins -- I-type lectins -- Galectins -- Microbial lectins: hemagglutinins, adhesins, and toxins -- Proteins that bind sulfated glycosaminoglycans -- Glycans in physiology and disease. Glycans in glycoprotein quality control -- Free glycans as signaling molecules -- Glycans in systemic physiology -- Bacterial and viral infections -- Parasitic infections -- Genetic disorders of glycan degradation -- Genetic disorders of glycosylation -- Glycans in acquired human diseases -- Glycosylation changes in cancer -- Methods and applications. Glycanr-recognizing probes as tools -- Glycosylation mutants of cultured mammalian cells -- Structural analysis of glycans -- Glycomics and glycoproteomics -- Glycoinformatics -- Chemical synthesis of glycans and glycoconjugates -- Chemoenzymatic synthesis of glycans and glycoconjugates -- Chemical tools for inhibiting glycosylation -- Glycosylation engineering -- Glycans in biotechnology and the pharmaceutical industry -- Glycans in nanotechnology -- Glycans in bioenergy and materials science -- Future directions in glycosciences -- Online appendices. Some important milestones in the history of glycobiology -- Symbol nomenclature for glycans (SNFG) -- Examples of GPI-anchored proteins -- Complex and varied structures of glycosylphosphatidylinositol (GPI) anchors -- Glycosylation genes essential for mouse embryonic development -- Comparison of two major classes of glycan-binding proteins -- Molecular dynamic simulations -- Known human glycosylation disorders -- Organizations and publications adopting SNFG
Control code
1003290722
Edition
Third edition.
Extent
1 online resource
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color), portraits (some color)
Specific material designation
remote
System control number
(OCoLC)1003290722
Label
Essentials of glycobiology, edited by Ajit Varki [and eleven others]
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
cr
Carrier MARC source
rdacarrier
Content category
  • text
  • still image
Content type code
  • txt
  • sti
Content type MARC source
  • rdacontent
  • rdacontent
Contents
General principles. Historical background and overview -- Monosaccharide diversity -- Oligosaccharides and polysaccharides -- Cellular organization of glycosylation -- Glycosylation precursors -- Glycosyltransferases and glycan-processing enzymes -- Biological functions of glycans -- A genomic view of glycobiology -- Structure and biosynthesis. N-glycans -- O-GalNAc glycans -- Glycosphingolipids -- Glycosylphosphatidylinositol anchors -- Other classes of eukaryotic glycans -- Structures common to different glycans -- Sialic acids and other nonulosonic acids -- Hyaluronan -- Proteoglycans and sulfated glycosaminoglycans -- Nucleocytoplasmic glycosylation -- The O-GlcNAc modification -- Glycans in evolution and development. Evolution of glycan diversity -- Eubacteria -- Archaea -- Fungi -- Viridiplantae and algae -- Nematoda -- Arthropoda -- Deuterostomes -- Glycan-binding proteins. Discovery and classification of glycan-binding protein -- Principles of glycan recognition -- Structural biology of glycan recognition -- R-type lectins -- L-type lectins -- P-type lectins -- C-type lectins -- I-type lectins -- Galectins -- Microbial lectins: hemagglutinins, adhesins, and toxins -- Proteins that bind sulfated glycosaminoglycans -- Glycans in physiology and disease. Glycans in glycoprotein quality control -- Free glycans as signaling molecules -- Glycans in systemic physiology -- Bacterial and viral infections -- Parasitic infections -- Genetic disorders of glycan degradation -- Genetic disorders of glycosylation -- Glycans in acquired human diseases -- Glycosylation changes in cancer -- Methods and applications. Glycanr-recognizing probes as tools -- Glycosylation mutants of cultured mammalian cells -- Structural analysis of glycans -- Glycomics and glycoproteomics -- Glycoinformatics -- Chemical synthesis of glycans and glycoconjugates -- Chemoenzymatic synthesis of glycans and glycoconjugates -- Chemical tools for inhibiting glycosylation -- Glycosylation engineering -- Glycans in biotechnology and the pharmaceutical industry -- Glycans in nanotechnology -- Glycans in bioenergy and materials science -- Future directions in glycosciences -- Online appendices. Some important milestones in the history of glycobiology -- Symbol nomenclature for glycans (SNFG) -- Examples of GPI-anchored proteins -- Complex and varied structures of glycosylphosphatidylinositol (GPI) anchors -- Glycosylation genes essential for mouse embryonic development -- Comparison of two major classes of glycan-binding proteins -- Molecular dynamic simulations -- Known human glycosylation disorders -- Organizations and publications adopting SNFG
Control code
1003290722
Edition
Third edition.
Extent
1 online resource
Form of item
online
Media category
computer
Media MARC source
rdamedia
Media type code
c
Other physical details
illustrations (some color), portraits (some color)
Specific material designation
remote
System control number
(OCoLC)1003290722

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