The Resource Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice, by Jie Ning, (electronic resource)
Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice, by Jie Ning, (electronic resource)
Resource Information
The item Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice, by Jie Ning, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice, by Jie Ning, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.
This item is available to borrow from 1 library branch.
- Summary
- Estrogen regulates skeletal muscle mass and function in female. Estrogen may influence skeletal muscle mass and function during development in males as estrogen receptors (ER) have been identified in both female and male skeletal muscle. Whether estrogen exerts its effects on skeletal muscle through estrogen receptor alpha (ER[alpha]) or beta (ER[beta]) or directly during development is unclear. The main purpose of this study was to determine ER knock-out effects on muscle mass and contractile function in muscle with different fiber types, in mature female and male mice that were either ER[alpha] knock out (ER-/-) or ER[beta]-/- with corresponding wild type (WT) groups as controls. Loss of ER[alpha] results in increased Gast and TA muscle in female mice whereas the muscle functions are not affected, and ER[alpha] also influences female Plan muscle function. In contrast, ER[beta] might not have effects on skeletal muscle in female mice. ER-/- and Ar-/- result in decreased Gast and TA muscle in male mice, suggesting that estrogen/ER[alpha] signaling might directly regulate male muscle growth, whereas the muscle function are not affected. In contrast, ER[beta] might not have any effects on skeletal muscle in male mice
- Language
- eng
- Note
-
- "August 2007"
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Vita
- Label
- Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice
- Title
- Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice
- Statement of responsibility
- by Jie Ning
- Subject
-
- Dissertations, Academic -- University of Missouri--Columbia -- Veterinary biomedical sciences
- Electronic books.
- Electronic bookss.
- Electronic dissertations
- Estrogen -- Physiological effect
- Estrogen -- Receptors
- Muscle contraction -- Regulation
- Aromatase -- Physiological effect
- Transgenic mice
- Muscles -- Metabolism
- Language
- eng
- Summary
- Estrogen regulates skeletal muscle mass and function in female. Estrogen may influence skeletal muscle mass and function during development in males as estrogen receptors (ER) have been identified in both female and male skeletal muscle. Whether estrogen exerts its effects on skeletal muscle through estrogen receptor alpha (ER[alpha]) or beta (ER[beta]) or directly during development is unclear. The main purpose of this study was to determine ER knock-out effects on muscle mass and contractile function in muscle with different fiber types, in mature female and male mice that were either ER[alpha] knock out (ER-/-) or ER[beta]-/- with corresponding wild type (WT) groups as controls. Loss of ER[alpha] results in increased Gast and TA muscle in female mice whereas the muscle functions are not affected, and ER[alpha] also influences female Plan muscle function. In contrast, ER[beta] might not have effects on skeletal muscle in female mice. ER-/- and Ar-/- result in decreased Gast and TA muscle in male mice, suggesting that estrogen/ER[alpha] signaling might directly regulate male muscle growth, whereas the muscle function are not affected. In contrast, ER[beta] might not have any effects on skeletal muscle in male mice
- Cataloging source
- MMU
- http://library.link/vocab/creatorName
- Ning, Jie
- Degree
- M.S.
- Dissertation year
- 2007.
- Granting institution
- University of Missouri-Columbia
- Illustrations
- illustrations
- Index
- no index present
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- theses
- http://library.link/vocab/relatedWorkOrContributorName
- Brown, Marybeth
- http://library.link/vocab/subjectName
-
- Estrogen
- Estrogen
- Transgenic mice
- Muscles
- Aromatase
- Muscle contraction
- Target audience
- specialized
- Label
- Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice, by Jie Ning, (electronic resource)
- Note
-
- "August 2007"
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Vita
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 182537850
- Dimensions
- unknown
- Form of item
- electronic
- Governing access note
- Access is limited to the campuses of the University of Missouri
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)182537850
- System details
- Mode of access: World Wide Web
- Label
- Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice, by Jie Ning, (electronic resource)
- Note
-
- "August 2007"
- The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
- Vita
- Bibliography note
- Includes bibliographical references
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Control code
- 182537850
- Dimensions
- unknown
- Form of item
- electronic
- Governing access note
- Access is limited to the campuses of the University of Missouri
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Specific material designation
- remote
- System control number
- (OCoLC)182537850
- System details
- Mode of access: World Wide Web
Subject
- Dissertations, Academic -- University of Missouri--Columbia -- Veterinary biomedical sciences
- Electronic books.
- Electronic bookss.
- Electronic dissertations
- Estrogen -- Physiological effect
- Estrogen -- Receptors
- Muscle contraction -- Regulation
- Aromatase -- Physiological effect
- Transgenic mice
- Muscles -- Metabolism
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.umsl.edu/portal/Estrogen-receptor-alpha-and-beta-knock-out/Se3bAHYXyGM/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.umsl.edu/portal/Estrogen-receptor-alpha-and-beta-knock-out/Se3bAHYXyGM/">Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice, by Jie Ning, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.umsl.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.umsl.edu/">University of Missouri-St. Louis Libraries</a></span></span></span></span></div>
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.umsl.edu/portal/Estrogen-receptor-alpha-and-beta-knock-out/Se3bAHYXyGM/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.umsl.edu/portal/Estrogen-receptor-alpha-and-beta-knock-out/Se3bAHYXyGM/">Estrogen receptor [alpha] and [beta] knock-out effects on skeletal muscle in mature female and male mice, and aromatase knock-out effects on skeletal muscle in mature male mice, by Jie Ning, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.umsl.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.umsl.edu/">University of Missouri-St. Louis Libraries</a></span></span></span></span></div>
