Coverart for item
The Resource Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists, Robert A. Copeland

Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists, Robert A. Copeland

Label
Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists
Title
Evaluation of enzyme inhibitors in drug discovery
Title remainder
a guide for medicinal chemists and pharmacologists
Statement of responsibility
Robert A. Copeland
Creator
Subject
Genre
Language
eng
Summary
Most enzymology textbooks, including his own, address biochemists and other researchers, says Copeland, a researcher in enzymology and mechanistic pharmacology at a large pharmaceutical corporation. Here he provides chemists and pharmacologists with key information to answer such questions as what opportunities for inhibitor interactions with enzym
Member of
Action
digitized
Cataloging source
N$T
http://library.link/vocab/creatorName
Copeland, Robert Allen
Dewey number
615/.19
Illustrations
illustrations
Index
index present
Language note
English
LC call number
QP601.5
LC item number
.C675 2005eb
Literary form
non fiction
NAL call number
381
NAL item number
M55 v. 46
Nature of contents
  • dictionaries
  • bibliography
NLM call number
  • W1
  • QU 143
NLM item number
  • ME9617 v.46 2005
  • C782e 2005
Series statement
Methods of biochemical analysis
Series volume
v. 46
http://library.link/vocab/subjectName
  • Enzyme inhibitors
  • Drugs
  • Enzyme inhibitors
  • Enzyme Inhibitors
  • Drug Design
  • Enzyme Inhibitors
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Drugs
  • Enzyminhibitoren
  • Arzneimittelentwicklung
  • Enzyminhibitor
Label
Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists, Robert A. Copeland
Instantiates
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Why enzymes as drug targets? -- Enzyme reaction mechanisms. -- Reversible modes of inhibitor interactions with enzymes. -- Assay considerations for compound library screening. -- Lead organization and structure-activity relationships for reversible inhibitors. -- Slow binding inhibitors. -- Tight binding inhibitors. -- Irreversible enzyme inactivators. -- Appendix 1. Kinetics if biochemical reactions. -- Appendix 2. Derivation of the enzyme-ligand binding isotherm equation. -- Appendix 3. Serial dilution schemes
Control code
58964965
Dimensions
unknown
Extent
1 online resource (xvii, 271 pages)
File format
unknown
Form of item
online
Isbn
9780471723264
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
http://library.link/vocab/ext/overdrive/overdriveId
ebl231747
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic reproduction.
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)58964965
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Label
Evaluation of enzyme inhibitors in drug discovery : a guide for medicinal chemists and pharmacologists, Robert A. Copeland
Publication
Antecedent source
unknown
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Why enzymes as drug targets? -- Enzyme reaction mechanisms. -- Reversible modes of inhibitor interactions with enzymes. -- Assay considerations for compound library screening. -- Lead organization and structure-activity relationships for reversible inhibitors. -- Slow binding inhibitors. -- Tight binding inhibitors. -- Irreversible enzyme inactivators. -- Appendix 1. Kinetics if biochemical reactions. -- Appendix 2. Derivation of the enzyme-ligand binding isotherm equation. -- Appendix 3. Serial dilution schemes
Control code
58964965
Dimensions
unknown
Extent
1 online resource (xvii, 271 pages)
File format
unknown
Form of item
online
Isbn
9780471723264
Level of compression
unknown
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations (some color).
http://library.link/vocab/ext/overdrive/overdriveId
ebl231747
Quality assurance targets
not applicable
Reformatting quality
unknown
Reproduction note
Electronic reproduction.
Sound
unknown sound
Specific material designation
remote
System control number
(OCoLC)58964965
System details
Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.

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      38.710138 -90.311107
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