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The Resource Integrating clinical research into epidemic response : the Ebola experience, Emily R. Busta, Michelle Mancher, Patricia A. Cuff, Keith McAdam, Gerald Keusch, editors ; Committee on Clinical Trials During the 2014-2015 Ebola Outbreak, Board on Global Health, Board on Health Sciences Policy, Health and Medicine Division ; a report of the National Academies of Sciences, Engineering, Medicine

Integrating clinical research into epidemic response : the Ebola experience, Emily R. Busta, Michelle Mancher, Patricia A. Cuff, Keith McAdam, Gerald Keusch, editors ; Committee on Clinical Trials During the 2014-2015 Ebola Outbreak, Board on Global Health, Board on Health Sciences Policy, Health and Medicine Division ; a report of the National Academies of Sciences, Engineering, Medicine

Editor
Contributor
Summary
The 2014-2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Republic of Congo (then Zaire) and South Sudan (then Sudan). However, because all Ebola outbreaks prior to that in West Africa in 2014-2015 were relatively isolated and of short duration, little was known about how to best manage patients to improve survival, and there were no approved therapeutics or vaccines. When the World Heath Organization declared the 2014-2015 epidemic a public health emergency of international concern in August 2014, several teams began conducting formal clinical trials in the Ebola affected countries during the outbreak. Integrating Clinical Research into Epidemic Response: The Ebola Experience assesses the value of the clinical trials held during the 2014-2015 epidemic and makes recommendations about how the conduct of trials could be improved in the context of a future international emerging or re-emerging infectious disease events
Language
eng
Work
Publication
Extent
1 online resource (1 PDF file (xxvi, 316 pages))
Contents
  • Introduction
  • Conducting clinical research during an epidemic
  • Assessment of therapeutic trials
  • Assessment of vaccine trials
  • Strengthening capacity for response and research
  • Engaging communities in research and response
  • Facilitating international coordination and collaboration
  • Appendices. Study approach and methods
  • Clinical trial designs
  • Ethical principles for research with human subjects
  • Biographical sketches of committee members and staff
Isbn
9780309457774
Instance
Label
Integrating clinical research into epidemic response : the Ebola experience
Title
Integrating clinical research into epidemic response
Title remainder
the Ebola experience
Statement of responsibility
Emily R. Busta, Michelle Mancher, Patricia A. Cuff, Keith McAdam, Gerald Keusch, editors ; Committee on Clinical Trials During the 2014-2015 Ebola Outbreak, Board on Global Health, Board on Health Sciences Policy, Health and Medicine Division ; a report of the National Academies of Sciences, Engineering, Medicine
Contributor
Editor
Subject
Language
eng
Summary
The 2014-2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Republic of Congo (then Zaire) and South Sudan (then Sudan). However, because all Ebola outbreaks prior to that in West Africa in 2014-2015 were relatively isolated and of short duration, little was known about how to best manage patients to improve survival, and there were no approved therapeutics or vaccines. When the World Heath Organization declared the 2014-2015 epidemic a public health emergency of international concern in August 2014, several teams began conducting formal clinical trials in the Ebola affected countries during the outbreak. Integrating Clinical Research into Epidemic Response: The Ebola Experience assesses the value of the clinical trials held during the 2014-2015 epidemic and makes recommendations about how the conduct of trials could be improved in the context of a future international emerging or re-emerging infectious disease events
Cataloging source
NLM
Dewey number
614.5/7
Funding information
This activity was supported by Contract No. HHSP233201400020B/HHSP23337042 with the Assistant Secretary for Preparedness and Response, U.S. Department of Health and Human Services. Any opinions, findings, conclusions, or recommendations expressed in this publication do not necessarily reflect the views of any organization or agency that provided support for the project.
Illustrations
illustrations
Index
no index present
LC call number
RC140.5
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • technical reports
NLM call number
  • 2017 G-897
  • WC 534
http://library.link/vocab/relatedWorkOrContributorName
  • Busta, Emily R.
  • Mancher, Michelle
  • Cuff, Patricia A.
  • McAdam, Keith P. W. J.
  • Keusch, Gerald
  • National Academies of Sciences, Engineering, and Medicine (U.S.)
http://library.link/vocab/subjectName
  • Ebola virus disease
  • Clinical trials
  • Hemorrhagic Fever, Ebola
  • Ebola Vaccines
  • Clinical Trials as Topic
  • Human Experimentation
  • Guinea
  • Liberia
  • Sierra Leone
  • MEDICAL
  • MEDICAL
  • MEDICAL
  • Clinical trials
  • West Africa
Label
Integrating clinical research into epidemic response : the Ebola experience, Emily R. Busta, Michelle Mancher, Patricia A. Cuff, Keith McAdam, Gerald Keusch, editors ; Committee on Clinical Trials During the 2014-2015 Ebola Outbreak, Board on Global Health, Board on Health Sciences Policy, Health and Medicine Division ; a report of the National Academies of Sciences, Engineering, Medicine
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Conducting clinical research during an epidemic -- Assessment of therapeutic trials -- Assessment of vaccine trials -- Strengthening capacity for response and research -- Engaging communities in research and response -- Facilitating international coordination and collaboration -- Appendices. Study approach and methods -- Clinical trial designs -- Ethical principles for research with human subjects -- Biographical sketches of committee members and staff
Control code
992788402
Dimensions
unknown
Extent
1 online resource (1 PDF file (xxvi, 316 pages))
Form of item
online
Isbn
9780309457774
Lccn
2017941808
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
color illustrations
Specific material designation
remote
System control number
(OCoLC)992788402
Label
Integrating clinical research into epidemic response : the Ebola experience, Emily R. Busta, Michelle Mancher, Patricia A. Cuff, Keith McAdam, Gerald Keusch, editors ; Committee on Clinical Trials During the 2014-2015 Ebola Outbreak, Board on Global Health, Board on Health Sciences Policy, Health and Medicine Division ; a report of the National Academies of Sciences, Engineering, Medicine
Publication
Copyright
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Conducting clinical research during an epidemic -- Assessment of therapeutic trials -- Assessment of vaccine trials -- Strengthening capacity for response and research -- Engaging communities in research and response -- Facilitating international coordination and collaboration -- Appendices. Study approach and methods -- Clinical trial designs -- Ethical principles for research with human subjects -- Biographical sketches of committee members and staff
Control code
992788402
Dimensions
unknown
Extent
1 online resource (1 PDF file (xxvi, 316 pages))
Form of item
online
Isbn
9780309457774
Lccn
2017941808
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
color illustrations
Specific material designation
remote
System control number
(OCoLC)992788402

Subject

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