Coverart for item
The Resource Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors

Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors

Label
Introduction to drug designing and development
Title
Introduction to drug designing and development
Statement of responsibility
Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors
Contributor
Subject
Language
eng
Summary
This book is useful to readers who are just beginning in the field of drug design and development. It starts with an introduction and some basic information about drugs. Pharmacokinetic and pharmacodynamic aspects are covered in the initial chapters. Systemic descriptions of pharmacokinetic parameters such as absorption, distribution, metabolism, and excretion are explained in simple and easy language. This book demonstrates detailed concepts of lead molecules and their sources. In addition, drug target classification, identification and validation strategies, as well as the design and develop
Member of
Cataloging source
E7B
Dewey number
615.1/9
Illustrations
illustrations
Index
index present
LC call number
RS122
LC item number
.I58 2014eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
NLM call number
QV 745
http://library.link/vocab/relatedWorkOrContributorName
  • Kumar, Rajnish
  • Sharma, Anju
  • Tiwari, Rajesh Kumar
Series statement
Pharmacology - research, safety testing and regulation
http://library.link/vocab/subjectName
  • Drugs
  • Pharmaceutical chemistry
  • Drug Design
  • MEDICAL
  • Drugs
  • Pharmaceutical chemistry
Label
Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors
Instantiates
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Acknowledgment; Contributors; Chapter 1 Drugs: Introduction and Definition; Abstract; Introduction; History; Basic Terminologies Related to Drugs; Drug Nomenclature; Adverse Effects of Drugs; Classification of Drugs; References; Chapter 2 Pharmacokinetics; Abstract; Introduction; ADME Properties; Rates of Reaction; Models Associated with Pharmacokinetics; Absorption; Distribution; Metabolism; Elimination; References
  • Chapter 3 PharmacodynamicsAbstract; Drug Receptor Theory; Occupation Theory; Mechanism of Drug Action; References; Chapter 4 Plants As a Source of Lead Molecules; Abstract; 1. Introduction; 2. System of Medicines; 3. Plant Metabolites; 4. Classification of Secondary Metabolites; 5. Terpenoids; 6. Alkaloids; 7. Non-Protein Amino Acids (NPAA's); 8. Polyketides; 9. Polyacetylenes; Conclusion; References; Chapter 5 Animals As a Source of Lead Molecules; Abstract; Introduction; Terrestrial Animals as Drug Resource; Marine Organism as Drug Resource
  • Impact of Indiscreet Animal Application for Medicinal PurposesFuture of Animals as Drug Resource; References; Chapter 6 Drug Targets and ValidationTechniques; Abstract; What Are Drug Targets?; Characteristics of Drug Targets; Classification of Drug Targets; Drug Target Identification; Direct Biochemical Methods; Genetic Interaction Methods; Computational Inference Methods; Drug Target Validation; References; Chapter 7 Screening of Drugs; Abstract; ADME Property; Virtual Screening; Methods of Virtual Screening; Conclusion; References; Chapter 8 Structure-Based Drug Designing; Abstract
  • Methods that Analyze the Active SiteMethods That Dock Whole Molecule; Connection Methods; References; Chapter 9 Concepts of Combinatorial Library; Abstract; 1. Introduction; 2. Combinatorial Chemistry Approaches; 3. Library Requirements; 4. Experimental Techniques in Combinatorial Chemistry; 5. Screening of Combinatorial Libraries; References; Chapter 10 Quantitative Structure Activity Relationship; Abstract; 1. Introduction; 2. Molecular Structure and Molecular Properties; 3. QSAR Equations; 4. Molecular Descriptors; 5. Free Wilson Analysis; 6. QSAR Modeling; 7. Three Dimensional (3D) Qsar
  • 8. Difference between Traditional QSAR and 3DQSARReferences; Chapter 11 Pharmacophore Modeling; Summary; History of Pharmacophore; Pharmacophore Based Drug Designing; Golden Rule of Six; Hip-Hop Theory; HypoGen Theory; Software/Tools for Pharmacophore modeling; References; Chapter 12 Drug Formulation and Dosage Forms; Abstract; Introduction; A Suitable Dosage Form -- Why?; Therapeutic Response and a Suitable Dosage Form; Salient Features of a Suitable Dosage Form; Challenges in Developing Suitable Dosage Form; Classification of Dosage Forms; References; Chapter 13 Drug Regulatory Affairs
Control code
868921927
Dimensions
unknown
Extent
1 online resource (292 pages)
Form of item
online
Isbn
9781629485713
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Specific material designation
remote
System control number
(OCoLC)868921927
Label
Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors
Publication
Copyright
Bibliography note
Includes bibliographical references and index
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
  • INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Acknowledgment; Contributors; Chapter 1 Drugs: Introduction and Definition; Abstract; Introduction; History; Basic Terminologies Related to Drugs; Drug Nomenclature; Adverse Effects of Drugs; Classification of Drugs; References; Chapter 2 Pharmacokinetics; Abstract; Introduction; ADME Properties; Rates of Reaction; Models Associated with Pharmacokinetics; Absorption; Distribution; Metabolism; Elimination; References
  • Chapter 3 PharmacodynamicsAbstract; Drug Receptor Theory; Occupation Theory; Mechanism of Drug Action; References; Chapter 4 Plants As a Source of Lead Molecules; Abstract; 1. Introduction; 2. System of Medicines; 3. Plant Metabolites; 4. Classification of Secondary Metabolites; 5. Terpenoids; 6. Alkaloids; 7. Non-Protein Amino Acids (NPAA's); 8. Polyketides; 9. Polyacetylenes; Conclusion; References; Chapter 5 Animals As a Source of Lead Molecules; Abstract; Introduction; Terrestrial Animals as Drug Resource; Marine Organism as Drug Resource
  • Impact of Indiscreet Animal Application for Medicinal PurposesFuture of Animals as Drug Resource; References; Chapter 6 Drug Targets and ValidationTechniques; Abstract; What Are Drug Targets?; Characteristics of Drug Targets; Classification of Drug Targets; Drug Target Identification; Direct Biochemical Methods; Genetic Interaction Methods; Computational Inference Methods; Drug Target Validation; References; Chapter 7 Screening of Drugs; Abstract; ADME Property; Virtual Screening; Methods of Virtual Screening; Conclusion; References; Chapter 8 Structure-Based Drug Designing; Abstract
  • Methods that Analyze the Active SiteMethods That Dock Whole Molecule; Connection Methods; References; Chapter 9 Concepts of Combinatorial Library; Abstract; 1. Introduction; 2. Combinatorial Chemistry Approaches; 3. Library Requirements; 4. Experimental Techniques in Combinatorial Chemistry; 5. Screening of Combinatorial Libraries; References; Chapter 10 Quantitative Structure Activity Relationship; Abstract; 1. Introduction; 2. Molecular Structure and Molecular Properties; 3. QSAR Equations; 4. Molecular Descriptors; 5. Free Wilson Analysis; 6. QSAR Modeling; 7. Three Dimensional (3D) Qsar
  • 8. Difference between Traditional QSAR and 3DQSARReferences; Chapter 11 Pharmacophore Modeling; Summary; History of Pharmacophore; Pharmacophore Based Drug Designing; Golden Rule of Six; Hip-Hop Theory; HypoGen Theory; Software/Tools for Pharmacophore modeling; References; Chapter 12 Drug Formulation and Dosage Forms; Abstract; Introduction; A Suitable Dosage Form -- Why?; Therapeutic Response and a Suitable Dosage Form; Salient Features of a Suitable Dosage Form; Challenges in Developing Suitable Dosage Form; Classification of Dosage Forms; References; Chapter 13 Drug Regulatory Affairs
Control code
868921927
Dimensions
unknown
Extent
1 online resource (292 pages)
Form of item
online
Isbn
9781629485713
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Specific material designation
remote
System control number
(OCoLC)868921927

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      38.710138 -90.311107
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