The Resource Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors
Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors
Resource Information
The item Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.
This item is available to borrow from 1 library branch.
- Summary
- This book is useful to readers who are just beginning in the field of drug design and development. It starts with an introduction and some basic information about drugs. Pharmacokinetic and pharmacodynamic aspects are covered in the initial chapters. Systemic descriptions of pharmacokinetic parameters such as absorption, distribution, metabolism, and excretion are explained in simple and easy language. This book demonstrates detailed concepts of lead molecules and their sources. In addition, drug target classification, identification and validation strategies, as well as the design and develop
- Language
- eng
- Extent
- 1 online resource (292 pages)
- Contents
-
- INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Acknowledgment; Contributors; Chapter 1 Drugs: Introduction and Definition; Abstract; Introduction; History; Basic Terminologies Related to Drugs; Drug Nomenclature; Adverse Effects of Drugs; Classification of Drugs; References; Chapter 2 Pharmacokinetics; Abstract; Introduction; ADME Properties; Rates of Reaction; Models Associated with Pharmacokinetics; Absorption; Distribution; Metabolism; Elimination; References
- Chapter 3 PharmacodynamicsAbstract; Drug Receptor Theory; Occupation Theory; Mechanism of Drug Action; References; Chapter 4 Plants As a Source of Lead Molecules; Abstract; 1. Introduction; 2. System of Medicines; 3. Plant Metabolites; 4. Classification of Secondary Metabolites; 5. Terpenoids; 6. Alkaloids; 7. Non-Protein Amino Acids (NPAA's); 8. Polyketides; 9. Polyacetylenes; Conclusion; References; Chapter 5 Animals As a Source of Lead Molecules; Abstract; Introduction; Terrestrial Animals as Drug Resource; Marine Organism as Drug Resource
- Impact of Indiscreet Animal Application for Medicinal PurposesFuture of Animals as Drug Resource; References; Chapter 6 Drug Targets and ValidationTechniques; Abstract; What Are Drug Targets?; Characteristics of Drug Targets; Classification of Drug Targets; Drug Target Identification; Direct Biochemical Methods; Genetic Interaction Methods; Computational Inference Methods; Drug Target Validation; References; Chapter 7 Screening of Drugs; Abstract; ADME Property; Virtual Screening; Methods of Virtual Screening; Conclusion; References; Chapter 8 Structure-Based Drug Designing; Abstract
- Methods that Analyze the Active SiteMethods That Dock Whole Molecule; Connection Methods; References; Chapter 9 Concepts of Combinatorial Library; Abstract; 1. Introduction; 2. Combinatorial Chemistry Approaches; 3. Library Requirements; 4. Experimental Techniques in Combinatorial Chemistry; 5. Screening of Combinatorial Libraries; References; Chapter 10 Quantitative Structure Activity Relationship; Abstract; 1. Introduction; 2. Molecular Structure and Molecular Properties; 3. QSAR Equations; 4. Molecular Descriptors; 5. Free Wilson Analysis; 6. QSAR Modeling; 7. Three Dimensional (3D) Qsar
- 8. Difference between Traditional QSAR and 3DQSARReferences; Chapter 11 Pharmacophore Modeling; Summary; History of Pharmacophore; Pharmacophore Based Drug Designing; Golden Rule of Six; Hip-Hop Theory; HypoGen Theory; Software/Tools for Pharmacophore modeling; References; Chapter 12 Drug Formulation and Dosage Forms; Abstract; Introduction; A Suitable Dosage Form -- Why?; Therapeutic Response and a Suitable Dosage Form; Salient Features of a Suitable Dosage Form; Challenges in Developing Suitable Dosage Form; Classification of Dosage Forms; References; Chapter 13 Drug Regulatory Affairs
- Isbn
- 9781629485713
- Label
- Introduction to drug designing and development
- Title
- Introduction to drug designing and development
- Statement of responsibility
- Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors
- Language
- eng
- Summary
- This book is useful to readers who are just beginning in the field of drug design and development. It starts with an introduction and some basic information about drugs. Pharmacokinetic and pharmacodynamic aspects are covered in the initial chapters. Systemic descriptions of pharmacokinetic parameters such as absorption, distribution, metabolism, and excretion are explained in simple and easy language. This book demonstrates detailed concepts of lead molecules and their sources. In addition, drug target classification, identification and validation strategies, as well as the design and develop
- Cataloging source
- E7B
- Dewey number
- 615.1/9
- Illustrations
- illustrations
- Index
- index present
- LC call number
- RS122
- LC item number
- .I58 2014eb
- Literary form
- non fiction
- Nature of contents
-
- dictionaries
- bibliography
- NLM call number
- QV 745
- http://library.link/vocab/relatedWorkOrContributorName
-
- Kumar, Rajnish
- Sharma, Anju
- Tiwari, Rajesh Kumar
- Series statement
- Pharmacology - research, safety testing and regulation
- http://library.link/vocab/subjectName
-
- Drugs
- Pharmaceutical chemistry
- Drug Design
- MEDICAL
- Drugs
- Pharmaceutical chemistry
- Label
- Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Acknowledgment; Contributors; Chapter 1 Drugs: Introduction and Definition; Abstract; Introduction; History; Basic Terminologies Related to Drugs; Drug Nomenclature; Adverse Effects of Drugs; Classification of Drugs; References; Chapter 2 Pharmacokinetics; Abstract; Introduction; ADME Properties; Rates of Reaction; Models Associated with Pharmacokinetics; Absorption; Distribution; Metabolism; Elimination; References
- Chapter 3 PharmacodynamicsAbstract; Drug Receptor Theory; Occupation Theory; Mechanism of Drug Action; References; Chapter 4 Plants As a Source of Lead Molecules; Abstract; 1. Introduction; 2. System of Medicines; 3. Plant Metabolites; 4. Classification of Secondary Metabolites; 5. Terpenoids; 6. Alkaloids; 7. Non-Protein Amino Acids (NPAA's); 8. Polyketides; 9. Polyacetylenes; Conclusion; References; Chapter 5 Animals As a Source of Lead Molecules; Abstract; Introduction; Terrestrial Animals as Drug Resource; Marine Organism as Drug Resource
- Impact of Indiscreet Animal Application for Medicinal PurposesFuture of Animals as Drug Resource; References; Chapter 6 Drug Targets and ValidationTechniques; Abstract; What Are Drug Targets?; Characteristics of Drug Targets; Classification of Drug Targets; Drug Target Identification; Direct Biochemical Methods; Genetic Interaction Methods; Computational Inference Methods; Drug Target Validation; References; Chapter 7 Screening of Drugs; Abstract; ADME Property; Virtual Screening; Methods of Virtual Screening; Conclusion; References; Chapter 8 Structure-Based Drug Designing; Abstract
- Methods that Analyze the Active SiteMethods That Dock Whole Molecule; Connection Methods; References; Chapter 9 Concepts of Combinatorial Library; Abstract; 1. Introduction; 2. Combinatorial Chemistry Approaches; 3. Library Requirements; 4. Experimental Techniques in Combinatorial Chemistry; 5. Screening of Combinatorial Libraries; References; Chapter 10 Quantitative Structure Activity Relationship; Abstract; 1. Introduction; 2. Molecular Structure and Molecular Properties; 3. QSAR Equations; 4. Molecular Descriptors; 5. Free Wilson Analysis; 6. QSAR Modeling; 7. Three Dimensional (3D) Qsar
- 8. Difference between Traditional QSAR and 3DQSARReferences; Chapter 11 Pharmacophore Modeling; Summary; History of Pharmacophore; Pharmacophore Based Drug Designing; Golden Rule of Six; Hip-Hop Theory; HypoGen Theory; Software/Tools for Pharmacophore modeling; References; Chapter 12 Drug Formulation and Dosage Forms; Abstract; Introduction; A Suitable Dosage Form -- Why?; Therapeutic Response and a Suitable Dosage Form; Salient Features of a Suitable Dosage Form; Challenges in Developing Suitable Dosage Form; Classification of Dosage Forms; References; Chapter 13 Drug Regulatory Affairs
- Control code
- 868921927
- Dimensions
- unknown
- Extent
- 1 online resource (292 pages)
- Form of item
- online
- Isbn
- 9781629485713
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations.
- Specific material designation
- remote
- System control number
- (OCoLC)868921927
- Label
- Introduction to drug designing and development, Rajnish Kumar, Anju Sharma and Rajesh Kumar Tiwari, editors
- Bibliography note
- Includes bibliographical references and index
- Carrier category
- online resource
- Carrier category code
-
- cr
- Carrier MARC source
- rdacarrier
- Color
- multicolored
- Content category
- text
- Content type code
-
- txt
- Content type MARC source
- rdacontent
- Contents
-
- INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; INTRODUCTION TO DRUG DESIGNING AND DEVELOPMENT; Library of Congress Cataloging-in-Publication Data; Contents; Preface; Acknowledgment; Contributors; Chapter 1 Drugs: Introduction and Definition; Abstract; Introduction; History; Basic Terminologies Related to Drugs; Drug Nomenclature; Adverse Effects of Drugs; Classification of Drugs; References; Chapter 2 Pharmacokinetics; Abstract; Introduction; ADME Properties; Rates of Reaction; Models Associated with Pharmacokinetics; Absorption; Distribution; Metabolism; Elimination; References
- Chapter 3 PharmacodynamicsAbstract; Drug Receptor Theory; Occupation Theory; Mechanism of Drug Action; References; Chapter 4 Plants As a Source of Lead Molecules; Abstract; 1. Introduction; 2. System of Medicines; 3. Plant Metabolites; 4. Classification of Secondary Metabolites; 5. Terpenoids; 6. Alkaloids; 7. Non-Protein Amino Acids (NPAA's); 8. Polyketides; 9. Polyacetylenes; Conclusion; References; Chapter 5 Animals As a Source of Lead Molecules; Abstract; Introduction; Terrestrial Animals as Drug Resource; Marine Organism as Drug Resource
- Impact of Indiscreet Animal Application for Medicinal PurposesFuture of Animals as Drug Resource; References; Chapter 6 Drug Targets and ValidationTechniques; Abstract; What Are Drug Targets?; Characteristics of Drug Targets; Classification of Drug Targets; Drug Target Identification; Direct Biochemical Methods; Genetic Interaction Methods; Computational Inference Methods; Drug Target Validation; References; Chapter 7 Screening of Drugs; Abstract; ADME Property; Virtual Screening; Methods of Virtual Screening; Conclusion; References; Chapter 8 Structure-Based Drug Designing; Abstract
- Methods that Analyze the Active SiteMethods That Dock Whole Molecule; Connection Methods; References; Chapter 9 Concepts of Combinatorial Library; Abstract; 1. Introduction; 2. Combinatorial Chemistry Approaches; 3. Library Requirements; 4. Experimental Techniques in Combinatorial Chemistry; 5. Screening of Combinatorial Libraries; References; Chapter 10 Quantitative Structure Activity Relationship; Abstract; 1. Introduction; 2. Molecular Structure and Molecular Properties; 3. QSAR Equations; 4. Molecular Descriptors; 5. Free Wilson Analysis; 6. QSAR Modeling; 7. Three Dimensional (3D) Qsar
- 8. Difference between Traditional QSAR and 3DQSARReferences; Chapter 11 Pharmacophore Modeling; Summary; History of Pharmacophore; Pharmacophore Based Drug Designing; Golden Rule of Six; Hip-Hop Theory; HypoGen Theory; Software/Tools for Pharmacophore modeling; References; Chapter 12 Drug Formulation and Dosage Forms; Abstract; Introduction; A Suitable Dosage Form -- Why?; Therapeutic Response and a Suitable Dosage Form; Salient Features of a Suitable Dosage Form; Challenges in Developing Suitable Dosage Form; Classification of Dosage Forms; References; Chapter 13 Drug Regulatory Affairs
- Control code
- 868921927
- Dimensions
- unknown
- Extent
- 1 online resource (292 pages)
- Form of item
- online
- Isbn
- 9781629485713
- Media category
- computer
- Media MARC source
- rdamedia
- Media type code
-
- c
- Other physical details
- illustrations.
- Specific material designation
- remote
- System control number
- (OCoLC)868921927
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