The Resource Maladaptation of cardiac and skeletal muscle in chronic disease : effects of exercise, by Robert Tyler Morris, (electronic resource)

Maladaptation of cardiac and skeletal muscle in chronic disease : effects of exercise, by Robert Tyler Morris, (electronic resource)

Label
Maladaptation of cardiac and skeletal muscle in chronic disease : effects of exercise
Title
Maladaptation of cardiac and skeletal muscle in chronic disease
Title remainder
effects of exercise
Statement of responsibility
by Robert Tyler Morris
Creator
Contributor
Thesis advisor
Subject
Genre
Language
eng
Summary
The human genome is adapted for daily physical activity (85). Thus, a sedentary lifestyle is capable of promoting detrimental consequences to human health. The linkage between lack of sufficient physical activity and the development of modern chronic disease began to evolve only in the second half of the 20th century. This relationship was initially documented in London where men, who were more sedentary at work or during leisure time, had higher rates of coronary heart disease (242 ; 243). A multitude of other published reports have since confirmed the health hazards of maintaining an inactive lifestyle (40; 329). In addition, modern chronic diseases attributed to physical inactivity now represent a major burden on direct health care costs in the United States which totaled 83.6 million dollars in 2000 (55; 102). The importance of physical activity has become more apparent and it is now recommended by the US Surgeon General that "every U.S. adult should accumulate 30 minutes or more of moderate-intensity physical activity on most, preferably all, days of the week" (264). Furthermore, physicians are also being recommended to prescribe regular exercise to sedentary patients as a measure to reduce chronic health conditions (40; 42). However, more experimental investigations are necessary to elucidate how exercise delays or inhibits the development of chronic diseases, including hypertension, obesity, and type II diabetes. Understanding the mechanisms that regulate such conditions may lead to a scientific basis for therapy and cure. The following studies were done to investigate: Part I) the regulation of cardiac structure and function by exercise in the hypertensive (mREN2)27 rat, and Part II) the effects of voluntary exercise on skeletal muscle lipids in an obese OLEFT rat. Lastly, Part III (supplemental) provides a brief discussion on the effects of caloric restriction in obesity
Cataloging source
MMU
http://library.link/vocab/creatorDate
1978-
http://library.link/vocab/creatorName
Morris, Robert Tyler
Degree
Ph. D.
Dissertation year
2007.
Granting institution
University of Missouri-Columbia
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Booth, Frank W.
http://library.link/vocab/subjectName
  • Exercise
  • Hypertension
  • Caloric Restriction
  • Chronic Disease
  • Heart
  • Lipid Metabolism
  • Muscle, Skeletal
  • Myocardium
  • Obesity
Target audience
specialized
Label
Maladaptation of cardiac and skeletal muscle in chronic disease : effects of exercise, by Robert Tyler Morris, (electronic resource)
Instantiates
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Vita
  • "August 2007"
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
182537895
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)182537895
System details
Mode of access: World Wide Web
Label
Maladaptation of cardiac and skeletal muscle in chronic disease : effects of exercise, by Robert Tyler Morris, (electronic resource)
Publication
Note
  • The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file
  • Vita
  • "August 2007"
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
multicolored
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Control code
182537895
Dimensions
unknown
Form of item
electronic
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Specific material designation
remote
System control number
(OCoLC)182537895
System details
Mode of access: World Wide Web

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