The Resource Management, and health status outcomes of obese patients with symptomatic peripheral artery disease : insight from the Portrait Registry, Peri-Okonny Allen Poghni

Management, and health status outcomes of obese patients with symptomatic peripheral artery disease : insight from the Portrait Registry, Peri-Okonny Allen Poghni

Label
Management, and health status outcomes of obese patients with symptomatic peripheral artery disease : insight from the Portrait Registry
Title
Management, and health status outcomes of obese patients with symptomatic peripheral artery disease
Title remainder
insight from the Portrait Registry
Statement of responsibility
Peri-Okonny Allen Poghni
Creator
Contributor
Author
Degree supervisor
Subject
Genre
Language
eng
Summary
Obesity is present in 36.2%, 20.4 % and 29.0% of adults in the US, Netherlands and Australia respectively. Obesity is a risk factor for cardiovascular disease and related complications. The management and health status implications of obesity in patients with peripheral artery disease (PAD) is unknown. Participants from The Patient-centered Outcomes Related to Treatment practices in peripheral Arterial disease: Investigating Trajectories (PORTRAIT), an international registry of patients presenting with new or worsening PAD symptoms to a vascular clinic, were included in this analysis. Weight and height at baseline and 12-month follow up were abstracted from patients' charts. BMIs (kg/m2) were categorized as normal (18.4 - 24.9), overweight (25 -29.9), and obese ({u2265} 30). PAD specific health status was assessed using the Peripheral Artery Disease Questionnaire Summary Score (PAQSS) at baseline and 12 months. Among obese participants, we abstracted information about referral to weight/diet counseling during the initial PAD visit and examined site variability in referral rates using hierarchical logistic regression to estimate median odds ratios (MOR). Multivariable linear regression, adjusting for demographics and comorbidities, was used to assess the relationship between obesity (vs. normal weight) and PAQ SS at baseline and 12 months. Linear regression models were replicated using BMI modeled as a continuous variable. Among 989 enrollees with documented BMI at baseline, the overall prevalence of obesity was 37%, but differed by country (41.4% USA, 19.5% Netherlands, 45.5% Australia, p =0.001). Only 21% of obese patient were referred to weight counseling. There was significant variability in referring overweight/obese participants for weight counselling across sites (range 0 - 41%, MOR = 3.3, 95% CI 2.0 - 7.3). Compared with normal weight, obesity was associated with worse PAQ summary score at baseline (mean difference= -7.2, 95% CI -10.4 to -4.1, p <0.01) and at 12 months (-7.4, 95% CI -11.4 to -3.5, p = 0.003), in unadjusted but not multivariable adjusted analysis accounting for demographics and smoking status (p > 0.05). In conclusion, the prevalence of obesity was higher among symptomatic PAD patients in the USA and Australia compared with the Netherlands and the general population of these countries. Referrals to weight counseling occurred only in 1 out of 5 obese patients. There was significant variability in weight counseling for obese/overweight participants, and obese patients consistently reported worse health status compared with normal weight patients. Obesity should be tested as a potential therapeutic target for comprehensive PAD management
Cataloging source
UMK
http://library.link/vocab/creatorDate
1985-
http://library.link/vocab/creatorName
Poghni, Peri-Okonny Allen
Degree
M.S.
Dissertation note
(School of Medicine).
Dissertation year
2018.
Granting institution
University of Missouri-Kansas City,
Illustrations
illustrations
Index
no index present
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • theses
http://library.link/vocab/relatedWorkOrContributorName
Smolderen, Kim G.
http://library.link/vocab/subjectName
  • Obesity
  • Peripheral vascular diseases
  • Obesity
  • Peripheral Arterial Disease
Label
Management, and health status outcomes of obese patients with symptomatic peripheral artery disease : insight from the Portrait Registry, Peri-Okonny Allen Poghni
Instantiates
Publication
Copyright
Note
  • "A thesis in Bioinformatics."
  • Advisor: Kim Smolderen
  • Vita
Antecedent source
not applicable
Bibliography note
Includes bibliographical references (pages 55-59)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
black and white
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Methodology -- Results -- Discussion -- Appendix
Control code
1085546507
Dimensions
unknown
Extent
1 online resource (60 pages)
File format
one file format
Form of item
online
Level of compression
mixed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Quality assurance targets
not applicable
Specific material designation
remote
System control number
(OCoLC)1085546507
System details
  • The full text of the thesis is available as an Adobe Acrobat .pdf file; Adobe Acrobat Reader required to view the file
  • Mode of access: World Wide Web
Label
Management, and health status outcomes of obese patients with symptomatic peripheral artery disease : insight from the Portrait Registry, Peri-Okonny Allen Poghni
Publication
Copyright
Note
  • "A thesis in Bioinformatics."
  • Advisor: Kim Smolderen
  • Vita
Antecedent source
not applicable
Bibliography note
Includes bibliographical references (pages 55-59)
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Color
black and white
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
Introduction -- Methodology -- Results -- Discussion -- Appendix
Control code
1085546507
Dimensions
unknown
Extent
1 online resource (60 pages)
File format
one file format
Form of item
online
Level of compression
mixed
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other physical details
illustrations.
Quality assurance targets
not applicable
Specific material designation
remote
System control number
(OCoLC)1085546507
System details
  • The full text of the thesis is available as an Adobe Acrobat .pdf file; Adobe Acrobat Reader required to view the file
  • Mode of access: World Wide Web

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