Coverart for item
The Resource Molecular signaling of mammalian inner ear development, Dorothy A. Frenz, editor, (electronic resource)

Molecular signaling of mammalian inner ear development, Dorothy A. Frenz, editor, (electronic resource)

Label
Molecular signaling of mammalian inner ear development
Title
Molecular signaling of mammalian inner ear development
Statement of responsibility
Dorothy A. Frenz, editor
Contributor
Subject
Language
eng
Summary
Annotation
Related
Member of
Cataloging source
YDX
Dewey number
617.8/82
LC call number
QL948
LC item number
.M65 2013
http://library.link/vocab/relatedWorkOrContributorName
Frenz, Dorothy A
Series statement
  • Human anatomy and physiology
  • Otolaryngology research advances
http://library.link/vocab/subjectName
  • Labyrinth (Ear)
  • Auditory pathways
  • Mammals
Summary expansion
The inner ear originates from an ectodermal thickening, the otic placode, which lies adjacent to the developing hindbrain. Complex interactions between regulatory signalling molecules guide development of the simple otic placode into the elaborate, multifunctional organs of hearing and balance. This book delves into recent research in the field, focusing on successive stages of inner ear development and how they are influenced by the co-ordinate activity of signalling molecules. This book begins with an overview of the evolutionary adaptation of the organ of Corti (organ of hearing) and the molecular signals that characterise ancestral development of the inner ear. Following this, the topics addressed include the complex signalling interactions underlying induction of the otic placode, key molecular mediators influencing inner ear development and patterning, genetic signalling of the vestibular (balance) system and clinical correlations to human balance disorders, commitment to auditory hair cell fate, and reliance of the inner ear on retinoic acid, a biologically-active derivative of vitamin A, for appropriate development. This timely and comprehensive book provides an excellent resource for researchers, clinician-scientists and students alike
Label
Molecular signaling of mammalian inner ear development, Dorothy A. Frenz, editor, (electronic resource)
Instantiates
Publication
Bibliography note
Includes bibliographical references and index
Control code
OCM1bookssj0001102858
Dimensions
26 cm.
Dimensions
unknown
Extent
viii, 178 p.
Isbn
9781626189928
Isbn Type
(hbk.)
Lccn
2013939130
Other physical details
ill.
Specific material designation
remote
System control number
(WaSeSS)ssj0001102858
Label
Molecular signaling of mammalian inner ear development, Dorothy A. Frenz, editor, (electronic resource)
Publication
Bibliography note
Includes bibliographical references and index
Control code
OCM1bookssj0001102858
Dimensions
26 cm.
Dimensions
unknown
Extent
viii, 178 p.
Isbn
9781626189928
Isbn Type
(hbk.)
Lccn
2013939130
Other physical details
ill.
Specific material designation
remote
System control number
(WaSeSS)ssj0001102858

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      38.710138 -90.311107
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