The Resource Predictors and consequences of severe hypoglycemia in adults with diabetes : a systematic review of the evidence, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center ; investigators: principal investigator, Hanna E. Bloomfield ... [et al.], (electronic resource)

Predictors and consequences of severe hypoglycemia in adults with diabetes : a systematic review of the evidence, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center ; investigators: principal investigator, Hanna E. Bloomfield ... [et al.], (electronic resource)

Label
Predictors and consequences of severe hypoglycemia in adults with diabetes : a systematic review of the evidence
Title
Predictors and consequences of severe hypoglycemia in adults with diabetes
Title remainder
a systematic review of the evidence
Statement of responsibility
prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center ; investigators: principal investigator, Hanna E. Bloomfield ... [et al.]
Contributor
Subject
Language
eng
Summary
Prevalence of type 2 diabetes is increasing at an alarming pace, fueled by the rising rates of overweight and obesity in many populations. In the VA healthcare system, the prevalence of diabetes was 20% in fiscal year 2000 and is now estimated at nearly 25%. Although people with diabetes have a substantially increased risk of cardiovascular disease (CVD), recent trials show that intensive glucose lowering does not reduce the risk of CVD death or all-cause mortality although it reduces the risk of microvascular complications (nephropathy, retinopathy and neuropathy) and possibly non-fatal myocardial infarction. Intensive glucose control also increases the risk of hypoglycemic episodes. Several recent meta-analyses of the trials comparing intensive to conventional glucose control concluded that intensive control is associated with a 2-2.5 fold increased risk of severe hypoglycemia. The reviews however have not included smaller randomized trials, trials focused on the comparison of specific drug regimens, and non-randomized trials. We conducted the current review to provide broader insight into the incidence of, the risk factors for, and the clinical and social impact of severe hypoglycemia in adults with type 2 diabetes treated with glucose lowering medications
Member of
Cataloging source
DNLM
NLM call number
WK 880
http://library.link/vocab/relatedWorkOrContributorName
  • Bloomfield, Hanna E
  • Quality Enhancement Research Initiative (U.S.)
  • Minneapolis VA Health Care System (U.S.)
Series statement
Evidence-based synthesis program
http://library.link/vocab/subjectName
  • Hypoglycemia
  • Diabetes Mellitus, Type 2
  • Blood Glucose
  • Glucose
  • Risk Factors
Label
Predictors and consequences of severe hypoglycemia in adults with diabetes : a systematic review of the evidence, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center ; investigators: principal investigator, Hanna E. Bloomfield ... [et al.], (electronic resource)
Instantiates
Publication
Note
"April 2012."
Bibliography note
Includes bibliographical references
Control code
OCM1bookssj0001013121
Dimensions
unknown
Specific material designation
remote
System control number
(WaSeSS)bookssj0001013121
Label
Predictors and consequences of severe hypoglycemia in adults with diabetes : a systematic review of the evidence, prepared for Department of Veterans Affairs, Veterans Health Administration, Quality Enhancement Research Initiative, Health Services Research & Development Service ; prepared by Evidence-based Synthesis Program (ESP) Center, Minneapolis VA Medical Center ; investigators: principal investigator, Hanna E. Bloomfield ... [et al.], (electronic resource)
Publication
Note
"April 2012."
Bibliography note
Includes bibliographical references
Control code
OCM1bookssj0001013121
Dimensions
unknown
Specific material designation
remote
System control number
(WaSeSS)bookssj0001013121

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