The Resource Protein conformational dynamics, Ke-li Han, Xin Zhang, Ming-jun Yang, editors, (electronic resource)
Protein conformational dynamics, Ke-li Han, Xin Zhang, Ming-jun Yang, editors, (electronic resource)
Resource Information
The item Protein conformational dynamics, Ke-li Han, Xin Zhang, Ming-jun Yang, editors, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.This item is available to borrow from 1 library branch.
Resource Information
The item Protein conformational dynamics, Ke-li Han, Xin Zhang, Ming-jun Yang, editors, (electronic resource) represents a specific, individual, material embodiment of a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.
This item is available to borrow from 1 library branch.
- Summary
-
- "This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression"--Publisher's description
- "This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression"--
- Language
- eng
- Contents
-
- Protein folding simulations by generalized-ensemble algorithms
- Application of Markov state models to simulate long timescale dynamics of biological macromolecules
- Understanding protein dynamics using conformational ensembles
- Generative models of conformational dynamics
- Generalized spring tensor models for protein fluctuation dynamics and conformational changes
- The joys and perils of flexible fitting
- Coarse-grained models of the proteins backbone conformational dynamics
- Simulating protein folding in different environmental conditions
- Simulating the peptide folding kinetic related spectra based on the Markov state model
- The dilemma of conformational dynamics in enzyme catalysis: perspectives from theory and experiment
- Exploiting intrinsic flexibility in drug design
- NMR and computational methods in the structural and dynamic characterization of ligand-receptor interactions
- Molecular dynamics simulation of membrane proteins
- Free-energy landscape of intrinsically disordered proteins investigated by all-atom multicanonical molecular dynamics
- Coordination and control inside simple biomolecular machines
- Multi-state targeting machinery govern the fidelity and efficiency of protein localization
- Molecular dynamics simulations of F1-ATPase
- Chemosensorial G-proteins-coupled receptors: a perspective from computational methods
- Isbn
- 9783319029696
- Label
- Protein conformational dynamics
- Title
- Protein conformational dynamics
- Statement of responsibility
- Ke-li Han, Xin Zhang, Ming-jun Yang, editors
- Language
- eng
- Summary
-
- "This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression"--Publisher's description
- "This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression"--
- Assigning source
- Publisher's description
- Cataloging source
- CDX
- Dewey number
- 570.3
- LC call number
- QP551
- LC item number
- .P76 2014
- NLM call number
-
- W1
- QU 55.9
- NLM item number
- AD559 v.805 2014
- http://library.link/vocab/relatedWorkOrContributorDate
- 1978-
- http://library.link/vocab/relatedWorkOrContributorName
-
- Han, Ke-Li
- Zhang, Xin
- Yang, Ming-jun
- Series statement
- Advances in experimental medicine and biology,
- Series volume
- volume 805
- http://library.link/vocab/subjectName
-
- Protein Conformation
- Molecular Dynamics Simulation
- Label
- Protein conformational dynamics, Ke-li Han, Xin Zhang, Ming-jun Yang, editors, (electronic resource)
- Bibliography note
- Includes bibliographical references and index
- Contents
- Protein folding simulations by generalized-ensemble algorithms -- Application of Markov state models to simulate long timescale dynamics of biological macromolecules -- Understanding protein dynamics using conformational ensembles -- Generative models of conformational dynamics -- Generalized spring tensor models for protein fluctuation dynamics and conformational changes -- The joys and perils of flexible fitting -- Coarse-grained models of the proteins backbone conformational dynamics -- Simulating protein folding in different environmental conditions -- Simulating the peptide folding kinetic related spectra based on the Markov state model -- The dilemma of conformational dynamics in enzyme catalysis: perspectives from theory and experiment -- Exploiting intrinsic flexibility in drug design -- NMR and computational methods in the structural and dynamic characterization of ligand-receptor interactions -- Molecular dynamics simulation of membrane proteins -- Free-energy landscape of intrinsically disordered proteins investigated by all-atom multicanonical molecular dynamics -- Coordination and control inside simple biomolecular machines -- Multi-state targeting machinery govern the fidelity and efficiency of protein localization -- Molecular dynamics simulations of F1-ATPase -- Chemosensorial G-proteins-coupled receptors: a perspective from computational methods
- Control code
- OCM1bookssj0001178944
- Dimensions
- unknown
- Isbn
- 9783319029696
- Isbn Type
- (alk. paper)
- Lccn
- 2014930165
- Specific material designation
- remote
- System control number
- (WaSeSS)bookssj0001178944
- Label
- Protein conformational dynamics, Ke-li Han, Xin Zhang, Ming-jun Yang, editors, (electronic resource)
- Bibliography note
- Includes bibliographical references and index
- Contents
- Protein folding simulations by generalized-ensemble algorithms -- Application of Markov state models to simulate long timescale dynamics of biological macromolecules -- Understanding protein dynamics using conformational ensembles -- Generative models of conformational dynamics -- Generalized spring tensor models for protein fluctuation dynamics and conformational changes -- The joys and perils of flexible fitting -- Coarse-grained models of the proteins backbone conformational dynamics -- Simulating protein folding in different environmental conditions -- Simulating the peptide folding kinetic related spectra based on the Markov state model -- The dilemma of conformational dynamics in enzyme catalysis: perspectives from theory and experiment -- Exploiting intrinsic flexibility in drug design -- NMR and computational methods in the structural and dynamic characterization of ligand-receptor interactions -- Molecular dynamics simulation of membrane proteins -- Free-energy landscape of intrinsically disordered proteins investigated by all-atom multicanonical molecular dynamics -- Coordination and control inside simple biomolecular machines -- Multi-state targeting machinery govern the fidelity and efficiency of protein localization -- Molecular dynamics simulations of F1-ATPase -- Chemosensorial G-proteins-coupled receptors: a perspective from computational methods
- Control code
- OCM1bookssj0001178944
- Dimensions
- unknown
- Isbn
- 9783319029696
- Isbn Type
- (alk. paper)
- Lccn
- 2014930165
- Specific material designation
- remote
- System control number
- (WaSeSS)bookssj0001178944
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<div class="citation" vocab="http://schema.org/"><i class="fa fa-external-link-square fa-fw"></i> Data from <span resource="http://link.umsl.edu/portal/Protein-conformational-dynamics-Ke-li-Han-Xin/WRwFpKtwnqI/" typeof="Book http://bibfra.me/vocab/lite/Item"><span property="name http://bibfra.me/vocab/lite/label"><a href="http://link.umsl.edu/portal/Protein-conformational-dynamics-Ke-li-Han-Xin/WRwFpKtwnqI/">Protein conformational dynamics, Ke-li Han, Xin Zhang, Ming-jun Yang, editors, (electronic resource)</a></span> - <span property="potentialAction" typeOf="OrganizeAction"><span property="agent" typeof="LibrarySystem http://library.link/vocab/LibrarySystem" resource="http://link.umsl.edu/"><span property="name http://bibfra.me/vocab/lite/label"><a property="url" href="http://link.umsl.edu/">University of Missouri-St. Louis Libraries</a></span></span></span></span></div>
