Coverart for item
The Resource Toxicity-pathway-based risk assessment : preparing for paradigm change : a symposium summary, Ellen Mantus, rapporteur ; Standing Committee on Risk Analysis Issues and Reviews, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies

Toxicity-pathway-based risk assessment : preparing for paradigm change : a symposium summary, Ellen Mantus, rapporteur ; Standing Committee on Risk Analysis Issues and Reviews, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies

Label
Toxicity-pathway-based risk assessment : preparing for paradigm change : a symposium summary
Title
Toxicity-pathway-based risk assessment
Title remainder
preparing for paradigm change : a symposium summary
Statement of responsibility
Ellen Mantus, rapporteur ; Standing Committee on Risk Analysis Issues and Reviews, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies
Creator
Contributor
Subject
Genre
Language
eng
Summary
In 2007, the National Research Council envisioned a new paradigm in which biologically important perturbations in key toxicity pathways would be evaluated with new methods in molecular biology, bioinformatics, computational toxicology, and a comprehensive array of in vitro tests based primarily on human biology. Although some considered the vision too optimistic with respect to the promise of the new science, no one can deny that a revolution in toxicity testing is under way. New approaches are being developed, and data are being generated. As a result, the U.S. Environmental Protection Agency (EPA) expects a large influx of data that will need to be evaluated. EPA also is faced with tens of thousands of chemicals on which toxicity information is incomplete and emerging chemicals and substances that will need risk assessment and possible regulation. Therefore, the agency asked the National Research Council to convene a symposium to stimulate discussion on the application of the new approaches and data in risk assessment. The symposium was held on May 11-13, 2009, in Washington, DC, and included presentations and discussion sessions on pathway-based approaches for hazard identification, applications of new approaches to mode-of-action analyses, the challenges to and opportunities for risk assessment in the changing paradigm, and future directions
Member of
Cataloging source
N$T
http://library.link/vocab/creatorName
Mantus, Ellen K
Dewey number
615.907
Funding information
This project was supported by Contract No. EP-C-06-057 between the National Academy of Sciences and the U.S. Environmental Protection Agency. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the author(s) and do not necessarily reflect the view of the organizations or agencies that provided support for this project.
Illustrations
illustrations
Index
no index present
LC call number
RA1221
LC item number
.R575 2010eb
Literary form
non fiction
Nature of contents
  • dictionaries
  • bibliography
  • technical reports
NLM call number
QV 602
http://library.link/vocab/relatedWorkOrContributorName
National Research Council (U.S.)
http://library.link/vocab/subjectName
  • Toxicology
  • Toxins
  • Toxicity testing
  • Health risk assessment
  • Risk management
  • Toxicity Tests
  • Risk Assessment
  • MEDICAL
  • Health risk assessment
  • Risk management
  • Toxicity testing
  • Toxicology
  • Toxins
Label
Toxicity-pathway-based risk assessment : preparing for paradigm change : a symposium summary, Ellen Mantus, rapporteur ; Standing Committee on Risk Analysis Issues and Reviews, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies
Instantiates
Publication
Note
Title from PDF title page
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
FrontMatter -- Preface -- Contents -- Summary of the Symposium -- Appendixes -- Appendix A: Biographic Information on the Standing Committee on Risk Analysis Issues and Reviews -- Appendix B: Biographic Information on the Planning Committee for a Symposium on Toxicity-Pathway-Based Risk Assessment -- Appendix C: Symposium Agenda -- Appendix D: Biographic Information on the Speakers and Panelists for a Symposium on Toxicity-Pathway-Based Risk Assessment -- Appendix E: Symposium Presentations -- Appendix F: Poster Abstracts
Control code
657413889
Dimensions
unknown
Extent
1 online resource (1 PDF file (xiv, 119 pages))
Form of item
online
Isbn
9780309154222
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
9786612660443
Other physical details
illustrations
http://library.link/vocab/ext/overdrive/overdriveId
266044
Specific material designation
remote
System control number
(OCoLC)657413889
Label
Toxicity-pathway-based risk assessment : preparing for paradigm change : a symposium summary, Ellen Mantus, rapporteur ; Standing Committee on Risk Analysis Issues and Reviews, Board on Environmental Studies and Toxicology, Division on Earth and Life Studies, National Research Council of the National Academies
Publication
Note
Title from PDF title page
Bibliography note
Includes bibliographical references
Carrier category
online resource
Carrier category code
  • cr
Carrier MARC source
rdacarrier
Content category
text
Content type code
  • txt
Content type MARC source
rdacontent
Contents
FrontMatter -- Preface -- Contents -- Summary of the Symposium -- Appendixes -- Appendix A: Biographic Information on the Standing Committee on Risk Analysis Issues and Reviews -- Appendix B: Biographic Information on the Planning Committee for a Symposium on Toxicity-Pathway-Based Risk Assessment -- Appendix C: Symposium Agenda -- Appendix D: Biographic Information on the Speakers and Panelists for a Symposium on Toxicity-Pathway-Based Risk Assessment -- Appendix E: Symposium Presentations -- Appendix F: Poster Abstracts
Control code
657413889
Dimensions
unknown
Extent
1 online resource (1 PDF file (xiv, 119 pages))
Form of item
online
Isbn
9780309154222
Media category
computer
Media MARC source
rdamedia
Media type code
  • c
Other control number
9786612660443
Other physical details
illustrations
http://library.link/vocab/ext/overdrive/overdriveId
266044
Specific material designation
remote
System control number
(OCoLC)657413889

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