Protein conformational dynamics

Resource Information

The work Protein conformational dynamics represents a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.

Label

Protein conformational dynamics

Statement of responsibility

Ke-li Han, Xin Zhang, Ming-jun Yang, editors

Contributor

• Han, Ke-Li
• Yang, Ming-jun
• Zhang, Xin, 1978-

Subject

• Molecular Dynamics Simulation
• Protein Conformation

Language

eng

Summary

• "This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression"--Publisher's description
• "This book discusses how biological molecules exert their function and regulate biological processes, with a clear focus on how conformational dynamics of proteins are critical in this respect. In the last decade, the advancements in computational biology, nuclear magnetic resonance including paramagnetic relaxation enhancement, and fluorescence-based ensemble/single-molecule techniques have shown that biological molecules (proteins, DNAs and RNAs) fluctuate under equilibrium conditions. The conformational and energetic spaces that these fluctuations explore likely contain active conformations that are critical for their function. More interestingly, these fluctuations can respond actively to external cues, which introduces layers of tight regulation on the biological processes that they dictate. A growing number of studies have suggested that conformational dynamics of proteins govern their role in regulating biological functions, examples of this regulation can be found in signal transduction, molecular recognition, apoptosis, protein / ion / other molecules translocation and gene expression"--

Member of

• Advances in experimental medicine and biology, v. 805.

Assigning source

Publisher's description

Cataloging source

CDX

Dewey number

570.3

LC call number

QP551

LC item number

.P76 2014

NLM call number

• W1
• QU 55.9

NLM item number

AD559 v.805 2014

Series statement

Advances in experimental medicine and biology,

Series volume

volume 805