G protein signaling mechanisms in the retina

Resource Information

The work G protein signaling mechanisms in the retina represents a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries.

Label

G protein signaling mechanisms in the retina

Statement of responsibility

Kirill A. Martemyanov, Alapakkam P. Sampath, editors

Contributor

• Martemyanov, Kirill A
• Sampath, Alapakkam P

Subject

• GTP-Binding Proteins -- physiology
• Vision, Ocular -- physiology
• Visual Pathways

Language

eng

Summary

• We have learned a great deal about the organization and function of GPCR pathways, and the role that they play in vision. The information gained from these studies has provided, and will continue to provide, critical insights to further our understanding of complex GPCR pathways in the central nervous and endocrine systems. In essence, the retina is the first ?optogenetically?-driven circuit with clearly understood physiology. Thus, studying GPCR-driven pathways in the retina will likely guide the interpretation of optogenetic experiments, which are increasingly utilized to study central circuits. Collectively, these signaling pathways allow the retina to represent visual space over a wide range of light intensities and to synchronize its function to the day/night cycle. G protein Signaling Mechanisms in the Retina summarizes our current understanding of the organizational principles of GPCR pathways, using insights derived from the study of the retina. The book highlights several G protein signaling cascades, including phototransduction, ON bipolar cell signaling, dopaminergic pathways, and ipRGC signaling
• We have learned a great deal about the organization and function of GPCR pathways, and the role that they play in vision. The information gained from these studies has provided, and will continue to provide, critical insights to further our understanding of complex GPCR pathways in the central nervous and endocrine systems. In essence, the retina is the first ?optogenetically?-driven circuit with clearly understood physiology. Thus, studying GPCR-driven pathways in the retina will likely guide the interpretation of optogenetic experiments, which are increasingly utilized to study central circuits. Collectively, these signaling pathways allow the retina to represent visual space over a wide range of light intensities and to synchronize its function to the day/night cycle. G protein Signaling Mechanisms in the Retina summarizes our current understanding of the organizational principles of GPCR pathways, using insights derived from the study of the retina. The book highlights several G protein signaling cascades, including phototransduction, ON bipolar cell signaling, dopaminergic pathways, and ipRGC signaling. --

Member of

• Springer series in vision research, 3

Assigning source

Source other than Library of Congress

Cataloging source

YDXCP

Dewey number

573.8/828

LC call number

QP479

LC item number

.G26 2014

NLM call number

• 2014 N-309
• WW 150

Series statement

Springer series in vision research

Series volume

volume 3