Study of antimicrobial activity and mechanism of zinc oxide nanoparticles against foodborne pathogens

Resource Information

The work Study of antimicrobial activity and mechanism of zinc oxide nanoparticles against foodborne pathogens represents a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries. This resource is a combination of several types including: Work, Language Material, Books.

Label

Study of antimicrobial activity and mechanism of zinc oxide nanoparticles against foodborne pathogens

Statement of responsibility

by Yang Liu

Creator

• Liu, Yang, 1985-

Contributor

• Li, Mengs̀hi

Thesis advisor

• Li, Mengs̀hi

Subject

• Antifungal agents
• Apple blue mold
• Botrytis cinerea
• Dissertations, Academic -- University of Missouri--Columbia -- Food science
• Electron microscopy
• Electronic books
• Electronic bookss
• Electronic dissertations
• Anti-infective agents
• Foodborne diseases -- Prevention
• Raman spectroscopy
• Zinc oxide
• Escherichia coli

Genre

• Electronic bookss
• Electronic dissertations
• Electronic books

Language

eng

Summary

Antimicrobial activities of zinc oxide nanoparticles (ZnO NPs) and their mode of action against an important foodborne bacterium (E. coli O157:H7) and two postharvest pathogenic fungi (Botrytis cinerea and were investigated in this study. ZnO NPs with sizes of 70 [plus or minus] 15 nm and concentrations from 0 to 12 mmol l-1 were used in this study. A battery of methods including traditional microbiological plating, scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Raman spectroscopy were used to study of ZnO NPs and to characterize the changes in morphology and cellular compositions of bacterial and fungal cells treated with ZnO NPs. Results show that ZnO NPs at concentrations greater than 3 mmol l−1 can significantly inhibit the growth of both bacteria and fungi. The inhibitory effects of ZnO NPs against E. coli O157:H7 increased as the concentration of ZnO NPs increased. Results indicate that ZnO NPs may distort and damage bacterial cell membrane, resulting in a leakage of intracellular contents and eventually the death of bacterial cells. P. expansum was more sensitive to the treatment with ZnO NPs than B. cinerea. SEM images and Raman spectra obtained in this study indicate two different antifungal mechanisms of ZnO NPs against B. cinerea and P. expansum. ZnO NPs inhibited the growth of B. cinerea by releasing nucleic acids, which caused tumor-like structures

Cataloging source

MUU

Degree

M.S.

Dissertation year

2009.

Granting institution

University of Missouri-Columbia

Illustrations

illustrations

Index

no index present

Literary form

non fiction

Nature of contents

• dictionaries
• bibliography
• theses

Target audience

specialized