Antimicrobials : new and old molecules in the fight against multi-resistant bacteria

Resource Information

The work Antimicrobials : new and old molecules in the fight against multi-resistant bacteria represents a distinct intellectual or artistic creation found in University of Missouri-St. Louis Libraries. This resource is a combination of several types including: Work, Language Material, Books.

Label

Antimicrobials : new and old molecules in the fight against multi-resistant bacteria

Title remainder

new and old molecules in the fight against multi-resistant bacteria

Statement of responsibility

Flavia Marinelli, Olga Genilloud, editors

Contributor

• Marinelli, Flavia
• Genilloud, Olga

Editor

• Marinelli, Flavia
• Genilloud, Olga

Subject

• Anti-infective agents
• Anti-Infective Agents
• Anti-infective agents
• MEDICAL -- Pharmacology

Language

eng

Summary

Reports on the emergence and prevalence of resistant bacterial infections in hospitals and communities raise concerns that we may soon no longer be able to rely on antibiotics as a way to control infectious diseases. Effective medical care would require the constant introduction of novel antibiotics to keep up in the "arms race" with resistant pathogens. This book closely examines the latest developments in the field of antibacterial research and development. It starts with an overview of the growing prevalence of resistant Gram-positive and Gram-negative pathogens, including their various resistance mechanisms, prevalence, risk factors and therapeutic options. The focus then shifts to a comprehensive description of all major chemical classes with antibacterial properties, their chemistry, mode of action, and the generation of analogs; information that provides the basis for the design of improved molecules to defeat microbial infections and combat the emerging resistances. In closing, recently developed compounds already in clinical use, those in preclinical or first clinical studies, and a number of promising targets to be exploited in the discovery stage are discussed

Cataloging source

GW5XE

Dewey number

615.7/92

Illustrations

illustrations

Index

index present

LC call number

RM267

Literary form

non fiction

Nature of contents

• dictionaries
• bibliography

NLM call number

QV 250